Frontal subcutaneous lipoma associated with large interhemispheric lipoma and corpus callosum agenesis

Abstract

Intracranial lipomas are extremely rare fat-containing lesions that comprise 0.1%-0.5% of all primary brain tumors. They are congenital lesions that arise due to persistence and maldifferentiation of the meninx primitive (subarachnoid space precursor). We report a case of a 30-year-old woman who presented with seizures due to an intracranial lipoma and no neurological deficits. CT (computerized tomography) imaging findings demonstrated a large interhemispheric partially calcified lipoma that communicated with a large scalp lipoma and was associated with agenesis of the corpus callosum. Compared to the prior CT imaging, the lipoma increased in size from 3.4 cm to 4.1 cm transversely. A recent CT angiogram done due to suspicion of an aneurysm showed the lipoma now measuring 6 cm by 4.7 cm. Most cases of intracranial lipoma have been reported in the pediatric age group. Here, we report a rare case of interhemispheric intracranial lipoma in the adult age group. This case also demonstrates the importance of imaging modalities for detecting intracranial lipoma without performing invasive brain biopsy.

Neuroimaging Spectrum of Intracranial Lipomas

“…Intracranial lipomas are uncommon congenital lesions [ 2 ]. They are a rare finding, found between 0.08% and 0.46% of the time in an autopsy series [ 3 ].…”

“…There are a few studies that have assessed the prevalence and location, but these are done for the western population. Few rare case reports of intracranial lipomas [ 2 ] have been reported in India, but a systematic review to assess their prevalence was lacking. Previous autopsy series have shown intracranial lipomas to be very rare lesions.…”