Frontiers in Cardiovascular Magnetic Resonance

Fuster, Valentín; Kim, Raymond J.

doi:10.1161/01.cir.0000155618.37779.a0

Cited by 95 publications

(68 citation statements)

References 100 publications

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“…For instance, although CMR is a highly attractive modality for the assessment of MI and viability, 22 some practical drawbacks potentially limit the impact of this technology for general clinical practice. In comparison to other imaging modalities, standard CMR is more complex: Patient and protocol setup times are longer, and multiple breath-holds and longer scanning times are necessary.…”

Section: Discussionmentioning

confidence: 99%

Rapid Detection of Myocardial Infarction by Subsecond, Free-Breathing Delayed Contrast-Enhancement Cardiovascular Magnetic Resonance

et al. 2007

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Background-An ultrafast, delayed contrast-enhancement cardiovascular magnetic resonance technique that can acquire subsecond, "snapshot" images during free breathing (subsecond) is becoming widely available. This technique provides myocardial infarction (MI) imaging with complete left ventricular coverage in Ͻ30 seconds. However, the accuracy of this technique is unknown. Methods and Results-We prospectively compared subsecond imaging with routine breath-hold delayed contrastenhancement cardiovascular magnetic resonance (standard) in consecutive patients. Two cohorts with unambiguous standards of truth were prespecified: (1) patients with documented prior MI (nϭ135) and (2)

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Section: Discussionmentioning

confidence: 99%

Rapid Detection of Myocardial Infarction by Subsecond, Free-Breathing Delayed Contrast-Enhancement Cardiovascular Magnetic Resonance

et al. 2007

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“…Direct visualization of the coronary arteries and thus assessment of wall thickness is becoming possible (83). Studies have proved that MR imaging is able to characterize several biochemically relevant parameters, such as water content, chemical composition, physical state, and molecular motion within the plaque (84).…”

Section: Advanced Molecular Imaging Applicationsmentioning

confidence: 99%

Hybrid PET/MR Imaging of the Heart: Potential, Initial Experiences, and Future Prospects

et al. 2013

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Learning Objectives: On successful completion of this activity, participants should be able to describe (1) advantages and shortcomings of hybrid PET/MR scanners with respect to cardiovascular applications (e.g. myocardial perfusion imaging and viability imaging), (2) additional value of the MR component in cardiac imaging, and (3) technical challenges and workflow considerations regarding hybrid PET/MR scanners in the field of cardiology (e.g. attenuation correction and cardiac/respiratory/patient motion).Financial Disclosure: Dr. Schwaiger is an investigator, meeting participant, and lecturer for Siemens Medical. The authors of this article have indicated no other relevant relationships that could be perceived as a real or apparent conflict of interest. CME Credit: SNMMI is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to sponsor continuing education for physicians. SNMMI designates each JNM continuing education article for a maximum of 2.0 AMA PRA Category 1 Credits. Physicians should claim only credit commensurate with the extent of their participation in the activity. For CE credit, participants can access this activity through the SNMMI Web site (http:// www.snmmi.org/ce_online) through March 2016.PET/CT and other combined scanners have in the past decade rapidly emerged as important research tools and are proving to be invaluable for improved diagnostics in routine nuclear medicine. The design of hybrid PET/MR scanners presented a formidable technical challenge, and only recently were these instruments introduced to the market. Initial expectations of the performance of these scanners have been high, notably because of the potential for superior tissue contrast inherent in the MR modality, as well as the potential for multiparametric functional imaging in conjunction with PET. However, the additional value and potential clinical role that these new systems might bring to the cardiac field have yet to be documented. This review presents a comparative summary of the existing applications for PET and MR in the field of cardiology and suggests potential cardiac applications exploiting unique properties of the newly introduced combined instrumentation. The diverse range of imaging modalities for cardiology includes echocardiography, CT, MR imaging, SPECT, and PET, each of which offers distinct properties and advantages. The demand for combined PET/CT instrumentation in clinical nuclear medicine has grown remarkably, because of the notable advantages presented by hybrid imaging with respect to anatomic localization of lesions. Although these advantages were initially driven by the demands of oncology imaging, the resultant broader availability of PET/CT has provided the opportunity to use these scanners for indications beyond oncology, such as in the field of cardiac imaging (1). Furthermore, CT images are necessary for rapid attenuation correction, which is of particular importance for quantification in myocardial perfusion imaging. Through the use of suitable CT components a...

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“…For the practical application of MR imaging in the diagnosis of vascular lesions, improvement of techniques to analyze MR information and the development of contrast media are necessary, along with improvement of equipment that can be used to obtain information quickly 3) .…”

Section: Introductionmentioning

confidence: 99%

“…Gadofluorine (Gd) detected macrophage-rich lesions of atherosclerotic plaques 15) . Other Gd-based contrast media have been developed to detect specific components such as platelets, angiogenesis markers and fibrin, and they have been used successfully to characterize plaques 3) . Recently, Evans blue-conjugated Gd was reported to enhance injured arteries 16) .…”

Section: Introductionmentioning

confidence: 99%

A Novel Contrast Medium Detects Increased Permeability of Rat Injured Carotid Arteries in Magnetic Resonance T2 Mapping Imaging

Imai

Kaneko

Asano

et al. 2007

JAT

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Aim: Aim of this study was to directly detect increased permeability of vascular lesions by magnetic resonance imaging. Methods: A novel contrast medium with a mean hydrodynamic diameter of 100 nm was prepared from monodispersed iron colloids incorporated into micelles of block copolymers composed of polyethylene glycol and polyamino acid. T2 mapping was applied to differentiate the minimal shortening of T2 relaxation time in balloon-injured rat carotid arteries. Results: The novel contrast medium accumulated in deendothelialized arteries. T2 relaxation times of injured and uninjured arteries were 50.6 9.5 ms and 26.9 2.4 ms, respectively (the mean SD, p 0.01, n 5). The novel contrast medium, but not commercially available contrast media, shortened the T2 relaxation time of the injured artery to 35.5 9.7 ms (p 0.01, n 4). Conclusion: A novel iron contrast medium enhanced the lesions with increased permeability. The contrast medium in combination with T2 mapping may be useful to detect unstable atherosclerotic plaques. J Atheroscler

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Frontiers in Cardiovascular Magnetic Resonance

Cited by 95 publications

References 100 publications

Rapid Detection of Myocardial Infarction by Subsecond, Free-Breathing Delayed Contrast-Enhancement Cardiovascular Magnetic Resonance

Rapid Detection of Myocardial Infarction by Subsecond, Free-Breathing Delayed Contrast-Enhancement Cardiovascular Magnetic Resonance

Hybrid PET/MR Imaging of the Heart: Potential, Initial Experiences, and Future Prospects

A Novel Contrast Medium Detects Increased Permeability of Rat Injured Carotid Arteries in Magnetic Resonance T2 Mapping Imaging

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