Fructooligosaccharides improve bone mass and biomechanical properties in rats

Lobo, Alexandre Rodrigues; Colli, Célia; Filisetti, Tullia Maria Clara Caterina

doi:10.1016/j.nutres.2006.06.019

Cited by 59 publications

(35 citation statements)

References 39 publications

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“…Although many authors indicate that prebiotic saccharides favourably influence lipid metabolism (Parks, 2002) and mineral absorption (Lobo et al, 2006) our results did not demonstrate such effects. CEL addition led to a significant increase in serum urea.…”

Section: Discussioncontrasting

confidence: 99%

Effects of inulin supplemented to cellulose-free or cellulose-rich diets on caecal environment and biochemical blood parameters in rats

Juśkiewicz¹,

Wróblewska²,

Jarosławska³

et al. 2009

J. Anim. Feed Sci.

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The effects of feeding soluble dietary fibre (inulin, I) separately or in combination with insoluble fibre (cellulose, CEL) on caecal fermentation and biochemical blood parameters were studied in rats. Four diets: CEL-rich (10%) and CEL-free, each supplemented with 5% of sucrose or I (CR, CF, CRI and CFI diets, respectively) were fed over 4 weeks, each to 10 male growing Wistar rats. Supplementation with I caused the increase of the mass of caecal tissue and digesta (only on CF diet, interaction at P<0.01 and P<0.05, respectively), modification of short-chain fatty acids profile, decrease of caecal pH and ammonia concentration, increase of Bifidobacteria and depression of E. coli number, and decrease of β-glucuronidase activity. Feeding CEL reduced ammonia and total SCFA concentration and activity of all enzymes, particularly β-galactosidase, did not affect microbial population but slightly decreased number of anaerobic saccharolytic and proteolytic bacteria spores. Interactive effects of I and CEL were found for the concentration of branched-chain fatty acids which was more depressed by I on CF than on CR diet. Dietary treatments did not affect blood parameters.

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Section: Discussioncontrasting

confidence: 99%

Effects of inulin supplemented to cellulose-free or cellulose-rich diets on caecal environment and biochemical blood parameters in rats

Juśkiewicz¹,

Wróblewska²,

Jarosławska³

et al. 2009

J. Anim. Feed Sci.

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“…Wheat grain contains oligosaccharides such as fructans and amiloxylans that facilitate the absorption of certain micronutrients (such as Fe and Zn) in the gut (Lobo et al, 2006). On the other hand, phytate (polyphosphates) and polyphenols, which are also present in wheat grain, inhibit the absorption of Zn and Fe (Brinch-Pedersen et al, 2007).…”

Section: Introductionmentioning

confidence: 99%

Wheat grain quality under increasing atmospheric CO2 concentrations in a semi-arid cropping system

Fernando

Panozzo²,

Tausz

et al. 2012

Journal of Cereal Science

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“…The relative increases in calcium, magnesium and phosphorus in the bone might be related to the indirect effect associated with microbial fermentation in the caecum, which is increased by inulin supplementation and volatile fatty acid production; this facilitates the absorption of minerals via trans epithelial transport due to induced pH decreases which changes the solubility of calcium, magnesium and phosphorus in the intestinal lumen, facilitating transport across the epithelium (Younes et al, 2001;Lobo et al, 2006;Scholz-Ahrens & Schrezenmeir, 2007). The short-chain fatty acids contribute directly to the increased absorption of calcium, phosphorus and magnesium through a cationexchange mechanism (Ladislav & Hannelore, 2005;Raschka & Daniel, 2005) and there is evidence that narrow bonds (tight junctions), located on the luminal side, adjacent to epithelial cells, regulate the absorption of several nutrients including calcium (Mineo et al, 2002;Pérez et al, 2008).…”

Section: Resultsmentioning

confidence: 99%

Inulin as a growth promoter in diets for rabbits

et al. 2013

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-Sixty New Zealand rabbits aged 40 days were divided into 4 groups of 15 animals. The control group received a free diet of antibiotic growth promoter (AGP) and inulin. The second group was supplemented with 2.5 g/kg of inulin. The third was administered AGP with 0.1 g/kg of flavomycin. Finally, the fourth group received a 2.5 and 0.1 g/kg inulin/AGP diet. Body weight gain was higher in the control group. Rabbits supplemented with inulin had lower values of triglycerides compared with the control and AGP groups, and their glucose level was significantly lower than those treated with AGP. Additionally, serum calcium and magnesium concentrations were higher than the other groups, particularly with regard to AGP. The bone content with regard to calcium, phosphorus and magnesium in the groups treated with inulin was higher compared with the control; moreover, phosphorus and magnesium were higher than in the AGP group. The thickness of the mucosa and crypt depth in the caecum were significantly higher in rabbits treated with inulin than in the other groups, but especially compared with the AGP group. Also, triglyceride values were lower for rabbits treated with inulin/AGP than for those treated with AGP and the bone magnesium concentration was significantly higher compared with the control group. In addition, inulin was shown to have positive effects on the rabbit, promoting increase in bone and serum calcium, magnesium and phosphorus, decrease in triglyceride levels, and improvement in the caecum (changes in morphology, crypt depth and mucosal thickness).

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Fructooligosaccharides improve bone mass and biomechanical properties in rats

Cited by 59 publications

References 39 publications

Effects of inulin supplemented to cellulose-free or cellulose-rich diets on caecal environment and biochemical blood parameters in rats

Effects of inulin supplemented to cellulose-free or cellulose-rich diets on caecal environment and biochemical blood parameters in rats

Wheat grain quality under increasing atmospheric CO2 concentrations in a semi-arid cropping system

Inulin as a growth promoter in diets for rabbits

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