Frühe Diagnose, Verlauf und Therapie der Retinopathie bei jugendlichen Diabetikern

Hövener, G.; Oberdisse, Ursula; Burger, W.; Weber, B.

doi:10.1007/978-3-642-87882-4_124

Cited by 3 publications

(3 citation statements)

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“…Higher prevalences have been reported from other populations (Brooser et al 1975;Hovener et al 1980;Blanksma et al 1983). The difference in prevalence figures may be partly due to the age distribution of the patients and to the different methods of examination.…”

Section: Discussionmentioning

confidence: 78%

Prevalence and risk factors of retinopathy in children with diabetes A population‐based study on Finnish children

Falck

Käär

Laatikainen

1993

Acta Ophthalmologica

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The prevalence of retinopathy in children with insulin-dependent diabetes mellitus (IDDM) was studied in a population-based survey on 194 of the 216 subjects (89.8%) with IDDM aged 4.6 to 16.6 years living in the county of Oulu, Finland. The diagnosis of retinopathy was based on fundus photography. The median age of the children was 12.2 years and the median duration of diabetes 4.5 years (range 0.14.2 years). Retinopathy was found in 21 (10.8%) of cases. All of the changes seen were mild and did not require treatment. All the children with retinopathy were pubertal or postpubertal, and an association was found between the presence of retinopathy and the long-term diabetes control, duration of diabetes, age and albuminuria. Logistic regression analysis showed increasing duration of diabetes, puberty and elevated blood glycated haemoglobin to be the main risk factors explaining the occurrence of retinopathy. In patients aged 13-16 years retinopathy was also related to female sex and diastolic blood pressure, but in logistic regression analysis duration of diabetes and glycated haemoglobin were the best predictors.

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Section: Discussionmentioning

confidence: 78%

Prevalence and risk factors of retinopathy in children with diabetes A population‐based study on Finnish children

Falck

Käär

Laatikainen

1993

Acta Ophthalmologica

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“…It has been suggested that the high figures (31-75%) presented by some authors based on angiography (Brooser et al 1975;Malone et al 1977;Hovener et al 1980;Blanksma et al 1983) could be due to 'overdiagnosis' by counting hyperfluorescent spots caused by PE defects in the prevalence of microangiopathy. According to our findings PE defects are, however, rare in young diabetics and therefore they may not explain the high prevalence rates of retinopathy presented.…”

Section: Discussionmentioning

confidence: 94%

White spots in the central fundus in diabetic children and adolescents

Falck

Laatikainen

1992

Acta Ophthalmologica

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Previously, small defects in the retinal pigment epithelium appearing as depigmented spots in the fundus photographs have been observed in a high proportion of adult diabetic patients. In order to evaluate whether these changes already occur in children we examined the black-and-white and colour fundus photographs of 206 diabetic children aged 4.6-19.6 years (median 12.6), with the median duration of diabetes of 4.7 years (range 0.0-14.2). Early signs of retinopathy were observed in 27 (13.1%) of them. The control group was composed of 45 healthy children aged 8.1-16.6 years (median 11.8). One or more tiny white spots in the fundus of one or both eyes were observed in 97 diabetics (47.1%), more often in those with retinopathy than in those without (66.7% vs. 44.1%, p less than 0.001). In the control group similar spots were observed in 24 children (53.5%). Only in a small proportion of children (4.4% of both diabetic and control patients) were the spots numerous. In children most of the white spots in the fundus may represent drusen type deposits rather than defects in the pigment epithelium.

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“…Bei freier Kost wird in der Regel nur einmal täglich Insulin gespritzt. In Deutschland tritt man für eine optimale Stoffwechselregulierung em (Hurter, 1977;Weber, 1975;u. a.…”

Section: Introductionunclassified

Diabetische Retinopathie bei Kindern und Jugendlichen. Ihre Abhängigkeit von der Stoffwechseleinstellung*

Hoffmann¹,

Gilde²,

Hürter³

et al. 1980

Klin Monatsbl Augenheilkd

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Ninety diabetics between eight and 18 years of age, whose diabetes is controlled very carefully, were examined by fluorescein angiography in order to investigate the incidence and severity of diabetic retinitis. At 21% the percentage was markedly lower than that found by other workers, who control metabolism much less stringently. Also the severity of the retinitis was found to be much less pronounced in our examinations than in those carried out by other groups. Our results show that besides disposition the control of diabetes plays a decisive role in the development of diabetic retinitis in young diabetics.

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Frühe Diagnose, Verlauf und Therapie der Retinopathie bei jugendlichen Diabetikern

Cited by 3 publications

References 1 publication

Prevalence and risk factors of retinopathy in children with diabetes A population‐based study on Finnish children

Prevalence and risk factors of retinopathy in children with diabetes A population‐based study on Finnish children

White spots in the central fundus in diabetic children and adolescents

Diabetische Retinopathie bei Kindern und Jugendlichen. Ihre Abhängigkeit von der Stoffwechseleinstellung*

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