FtsZ, A Tubulin Homologue Spatiotemporally Regulates the Bacterial Cell Division

Abstract

Most common pattern of Bacterial division is binary fission. Bacterial division occurs by the construction of Z-ring at appropriate time and at a defined site. FtsZ is the major component of Z-ring formation, and the polymerization of FtsZ is regulated in space and time by negative and positive regulators of FtsZ assembly. In the bacterial cell positive and negative regulators help in attaining a critical concentration gradient, such that at mid cell the critical concentration required for Z-ring formation is lowest, thus Z-ring formation takes place at this site only.