Fuchs-Endotheldystrophie, Katarakt und Astigmatismus

Hamon, Loïc; Berger, Tim; Seitz, Berthold; Daas, Loay

doi:10.1007/s00347-022-01591-w

Cited by 2 publications

References 8 publications

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Descemet Membrane Endothelial Keratoplasty after failed penetrating keratoplasty– case series and review of the literature

Wykrota,

Hamon,

Daas

et al. 2024

BMC Ophthalmol

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Background This study aims to evaluate visual outcome, central corneal thickness, and re-bubbling rate in a cohort with undersized sequential Descemet Membrane Endothelial Keratoplasty (DMEK) due to endothelial graft decompensation following primary penetrating keratoplasty (PK). Methods All patients who received a sequential DMEK (n = 16) or triple DMEK (n = 2) after failed primary PK between November 2020 and June 2022 were retrospectively evaluated. Analyzed parameters were corrected distance visual acuity (CDVA), central corneal thickness (CCT), re-bubbling rate and graft survival. Results 18 eyes of 18 patients were included. All patients underwent a DMEK with undersized graft after failed PK(s). Mean time between the last PK and DMEK was 102 ± 82 weeks. Mean follow-up time was 8.9 ± 4.6 months. CDVA increased significantly from 1.12 ± 0.60 logMAR preoperatively to 0.64 ± 0.49 logMAR 6 weeks postoperatively (p = 0.013). Mean CCT decreased significantly from 807 ± 224 μm before to 573 ± 151 μm 6 weeks after DMEK (p = 0.003). Re-bubbling was necessary in eight eyes (44.4%) after a median time of 7 days. The 12-month Kaplan Meier survival was 66.7%. Conclusion In case of endothelial graft decompensation without stromal scars after primary PK, a DMEK can be performed for selected patients who had satisfying CDVA before the endothelial decompensation. Prior to DMEK indication, an AS-OCT should routinely be performed to circularly search for posterior steps at the PK graft margin, as well as shortly after DMEK to exclude a detachment of the endothelial graft. All patients should be informed about a higher re-bubbling rate in comparison to primary DMEK.

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Descemet Membrane Endothelial Keratoplasty after failed penetrating keratoplasty– case series and review of the literature

Wykrota,

Hamon,

Daas

et al. 2024

BMC Ophthalmol

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Descemet Membrane Endothelial Keratoplasty after failed penetrating keratoplasty – Case series and review of the literature

Wykrota

Hamon

Daas

et al. 2023

Preprint

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Background This study aims to evaluate visual outcome, central corneal thickness, and re-bubbling rate in a cohort with undersized secondary Descemet Membrane Endothelial Keratoplasty (DMEK) due to endothelial graft decompensation following primary penetrating keratoplasty (PK). Methods All patients who received a secondary DMEK (n = 16) or triple DMEK (n = 2) after failed primary PK between November 2020 and June 2022 were retrospectively evaluated. Analyzed parameters were corrected distance visual acuity (CDVA), central corneal thickness (CCT), re-bubbling rate and graft survival. Results 18 eyes of 18 patients were included. All patients underwent a DMEK with undersized graft after failed PK(s). Mean time between the last PK and DMEK was 102 ± 82 weeks. CDVA increased significantly from 1.12 ± 0.60 logMAR preoperatively to 0.64 ± 0.49 logMAR 6 weeks postoperatively (p = 0.013). Mean CCT decreased significantly from 807 ± 224 µm before to 573 ± 151 µm 6 weeks after DMEK (p = 0.003). Re-bubbling was necessary in eight eyes (44.4%) after a median time of 7 days. The 12-month Kaplan Meier survival was 66.7%. Conclusion In case of endothelial graft decompensation without stromal scars after primary PK, a (triple) DMEK can be performed for patients who had satisfying CDVA before the endothelial decompensation. Prior to DMEK indication, an AS-OCT should be routinely performed to circularly search for posterior steps at the PK graft margin, as well as shortly after DMEK to exclude a detachment of the endothelial graft. All patients should be informed about a higher re-bubbling rate in comparison to primary DMEK.

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Fuchs-Endotheldystrophie, Katarakt und Astigmatismus

Cited by 2 publications

References 8 publications

Descemet Membrane Endothelial Keratoplasty after failed penetrating keratoplasty– case series and review of the literature

Descemet Membrane Endothelial Keratoplasty after failed penetrating keratoplasty– case series and review of the literature

Descemet Membrane Endothelial Keratoplasty after failed penetrating keratoplasty – Case series and review of the literature

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