Fuchs heterochromic iridocyclitis-associated glaucoma: a retrospective comparison of primary Ahmed glaucoma valve implantation and trabeculectomy with mitomycin C

Esfandiari, Hamed; Loewen, Nils A.; Hassanpour, Kiana; Fatourechi, Ali; Yazdani, Shahin; Wang, Chao; Yaseri, Mehdi; Pakravan, Mohammad

doi:10.12688/f1000research.15244.1

Cited by 9 publications

(3 citation statements)

References 45 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Bu nedenle hastaların takibinde erken glokom tanısı görsel prognoz açısından önem arz etmektedir (18). Bu konuda yapılan çalışmalar değerlendirildiğinde FHİ hastalarında glokom sıklığı %6,5-59 gibi geniş bir yelpazede görülmekte iken bu hastalarda genellikle trabekülektomi gibi cerrahi girişim ihtiyacı görülmektedir (4,17,19,20)…”

Section: Bulgularunclassified

Fuchs heterokromik iridosiklit hastalarında kornea biyomekaniği ve kornea değerlendirilmesi

et al. 2022

View full text Add to dashboard Cite

Aim: To evaluate cornea and corneal biomechanical properties of patients with Fuchs heterochromic iridocylitis. Materials and Methods: Fourteen FHI positive eyes (Group 1) and the contralateral healthy eyes (Group 2) were included. All patients underwent a detailed ophthalmic examination was performed. Also, Ocular Response Analyzer was used to detect corneal biomechanical properties, and specular microscopic evaluation for corneal endothelial cells count was performed. Results: The mean best corrected visual acuity and intraocular pressure were statistically similar. (p values were 0.077 and 0.557, respectively). Corneal biomechanical properties including corneal hysteresis, corneal resistance factor, IOPcc and IOPg were not statistically significant. (p values were 0.521, 0.817, 0.980 and 0.980, respectively). Mean central corneal thickness in Group 1 and 2 were 555.57±42.95 (467-626), 556.5±37.04 (480-623) micrometer, respectively. The difference was not statistically significant (p=0.959). Mean corneal endothelial cell density of Group 1 and Group 2 were 2313±420.22 (1271-2717) and 2404.42±326.75 (1566-2834) cells/mm2, respectively. The difference was not statistically significant (p=0.626). Conclusion: Conflicting with the literature, no differences were detected in corneal biomechanical properties, central corneal thickness and corneal endothelial cell density in Fuchs Heterochromic Iridocyclitis positive eyes. However, more studies with increasing number of patients are still needed.

show abstract

Section: Bulgularunclassified

Fuchs heterokromik iridosiklit hastalarında kornea biyomekaniği ve kornea değerlendirilmesi

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Raw data collected from all study participants. DOI: http://doi.org/10.5256/f1000research.15244.d207417 48 .…”

Section: Data Availabilitymentioning

confidence: 99%

Fuchs heterochromic iridocyclitis-associated glaucoma: a retrospective comparison of primary Ahmed glaucoma valve implantation and trabeculectomy with mitomycin C

et al. 2018

Self Cite

View full text Add to dashboard Cite

Background: The aim of this study was to compare the safety and efficacy of primary trabeculectomy with mitomycin C and Ahmed glaucoma valve (AGV) implantation in patients with Fuchs heterochromic iridocyclitis (FHIC)-related glaucoma, a rare complication of an uncommon form of uveitis. Methods : In this retrospective comparative case series, 26 FHIC-associated glaucoma patients received trabeculectomy (n=12) or an AGV (n=14). Primary outcome measures were surgical success, defined as intraocular pressure (IOP) ≤21 mmHg, decreasing ≥20% from baseline, and no secondary glaucoma surgery. Secondary outcome measures were the number of glaucoma medications, complications, best corrected visual acuity (BCVA), and IOP. Results: The follow-up was 34.0±17.7 months in patients that received trabeculectomy and 33.4±18.6 months in AGV (P= 0.837). The cumulative probability of success rate was 41.7% for trabeculectomy and 85.7% for AGV, with no significant difference in complications (P>0.05). The IOP in patients that received trabeculectomy dropped from 23.4±3.3 mmHg to 21.6±5.2 mmHg at the final visit (P= 0.041). In patients that received AGV, the IOP decreased from 24±7.8 to 17.1±2.6 mmHg (P= 0.003). The number of glaucoma medications at baseline were 3.3±0.5 in those that received trabeculectomy and 3±0.6 in those that received AGV (P=0.233), and decreased to 2.4±1.0 (P=0.008) and 1.7±0.6 (P=0.002), respectively. BCVA was equal in both groups and did not change (P>0.05). Conclusion: Primary AGV had a higher success rate than trabeculectomy, with patients also needing fewer medications for the management of FHIC-associated glaucoma.

show abstract

“…Although the average IOP following AGV is about 1.85 mmHg higher than in BI, a comparable success rate, fewer postoperative complication rates, and ease of handling are advantages of AGV over BI [4] . A downside of AGV is an increased rate of a hypertensive phase (HP) that can persist if not managed aggressively [10] with an incidence that ranges from 30% to 82% and starts one to 13 weeks postoperatively [10][11][12][13] . It has been speculated that early contact of aqueous inflammatory mediators with Tenon's capsule and the conjunctiva or early stretch [14] of the forming capsule may lead to this [10,15,16] .…”

Section: Introductionmentioning

confidence: 99%

Impact of same-session trabectome surgery on Ahmed glaucoma valve outcomes

Esfandiari

Shazly

Shah

et al. 2018

Graefes Arch Clin Exp Ophthalmol

Self Cite

View full text Add to dashboard Cite

Purpose: To evaluate the efficacy and survival rates of same session ab interno trabeculectomy with the trabectome and Ahmed glaucoma valve implant (AT) in comparison to the Ahmed glaucoma valve alone (A).Method : A total of 107 eyes undergoing primary glaucoma surgery were enrolled in this retrospective comparative case series, including 48 eyes which underwent AT and 59 eyes which received A alone . Participants were identified using the procedural terminology codes, and their medical records were reviewed. The primary outcome measure was surgical success, defined as intraocular pressure (IOP) > 5 mmHg, ≤ 21 mmHg, and IOP reduction ≥ 20% from baseline at two consecutive visits after three months, no reoperation for glaucoma. Secondary outcome measures were IOP, the number of glaucoma medications, incidence of a hypertensive phase, and best corrected visual acuity (BCVA). Results:The cumulative probability of success at one year was 70% in AT, and 65% in A (p=0.85). IOP decreased significantly from 26.6 ± 10.1 mmHg at baseline to 14.7 ± 3.3 mmHg at the final follow-up in AT (p= 0.001). The corresponding numbers for A were 28.8 ± 10.2 and 16.7 ± 4.9, respectively (p= 0.001). The final IOP was significantly lower in AT (p= 0.022). The number of medications at baseline was comparable in both groups (2.6 ± 1.2 in AT and 2.5 ± 1.3 in A, p=0.851). Corresponding number at 1 year visit was 1.2±2 in AT and 2.8±1.8 in A (p=0.001).The incidence of a hypertensive phase was 18.7% in AT and 35.5% in A (p=0.05). HP resolved in only 30% of eyes. The criteria for HP resolution were fulfilled in 9 eyes (30%). There was no difference in the rate of resolution of the hypertensive phase between AT and A (33.3% and 28.5%, respectively, p=0.67).Conclusion : Ahmed glaucoma valve implant with same session trabectome surgery significantly decreased the rate of the hypertensive phase and postoperative IOP as well as the number of glaucoma medications.

show abstract

Fuchs heterochromic iridocyclitis-associated glaucoma: a retrospective comparison of primary Ahmed glaucoma valve implantation and trabeculectomy with mitomycin C

Cited by 9 publications

References 45 publications

Fuchs heterokromik iridosiklit hastalarında kornea biyomekaniği ve kornea değerlendirilmesi

Fuchs heterokromik iridosiklit hastalarında kornea biyomekaniği ve kornea değerlendirilmesi

Fuchs heterochromic iridocyclitis-associated glaucoma: a retrospective comparison of primary Ahmed glaucoma valve implantation and trabeculectomy with mitomycin C

Impact of same-session trabectome surgery on Ahmed glaucoma valve outcomes

Contact Info

Product

Resources

About