Fuchs uveitis

Abstract

Fuchs uveitis (FU) is a frequent, chronic course of intraocular inflammation, which is associated with a gradual onset of decreased visual acuity. The clinical manifestation of the triad of heterochromia, cataract and glaucoma varies considerably. This explains the often delayed diagnosis. Although the aetiology and pathogenesis of the changes are still unclear, there is no doubt that infections play a significant role. Intraocular antibodies directed against rubella viruses show a high association with the disease pattern, and their detection can even be used to support the diagnosis. The treatment of FU is limited to symptomatic measures. Corticosteroids are usually only moderately effective and should be used with caution due to adverse effects, with progression of cataract and secondary glaucoma. The prognosis of the disease can be regarded as favourable and depends essentially on the secondary changes.

Intermediäre Uveitis bei Erwachsenen und Kindern – Update

“…Die Identifikation dieser Entität ist von großer Bedeutung, da die Therapiestrategien von FUS und intermediärer Uveitis sich deutlich unterscheiden. Gegebenenfalls kann eine Analyse von Kammerwasser mit Durchführung einer PCR (polymerase chain reaction) auf Virusgenom (vorrangig Zytomegalievirus oder Rubella) hilfreich zur differenzialdiagnostischen Abgrenzung sein [9].…”