This study delves
into the influence of incorporating alumina (Al
2
O
3
) nanoparticles with waste cooking oil (WCO)
biofuels in a gasoline engine that employs premixed fuel. During the
suction phase, gasoline blends with atmospheric air homogeneously
at the location of the inlet manifold. The biodiesel, enhanced with
Al
2
O
3
nanoparticles and derived from WCO, is
subsequently directly infused into the combustion chamber at 23°
before the top dead center. The results highlight that when gasoline
operates in the homogeneous charge compression ignition with direct
injection (HCCI-DI) mode, there is a notable enhancement in thermal
efficiency by 4.23% in comparison to standard diesel combustion. Incorporating
the Al
2
O
3
nanoparticles with the WCO biodiesel
contributes to an extra rise of 6.76% in thermal efficiency. Additionally,
HCCI-DI combustion paves the way for a reduction in nitrogen oxides
and smoke emissions, whereas biodiesel laced with Al
2
O
3
nanoparticles notably reduces hydrocarbon and carbon monoxide
discharges. Predictive tools such as artificial neural networks and
regression modeling were employed to forecast engine performance variables.