“…Enhanced growth achieved by interaction/synergism between or among nutrient sources per se and the role of specific aquafeed additives, as influenced by the characteristics of a specific production system, must be focal areas of investigation. For example, the beneficial effects of recognized dietary probiotic and prebiotic additives to sustainability as revealed through qualitative and quantitative changes in the microbiome (D'Abramo, 2018) must be weighed against the additional cost of inclusion.…”