Objective -The goal of this study was to evaluate the reliability of the Animal Rescue and Transportation Sling (ARTS) for emergency and clinical use in horses. Design -A retrospective study of the use of the ARTS in the hospital and field. Setting -The medical records of 158 horses referred to the Equine Hospital, University of Zurich, and 23 records from the Large Animal Rescue. Animals -The ARTS was used in 121 standing and 60 recumbent horses. Seventy-eight horses were sedated, 47 patients were under general anesthesia when the sling was applied and no sedation or anesthesia was required in 56 horses.Interventions and Main Results -The ARTS was applied in crane and helicopter rescue operations to stabilize horses that required lifting (n 5 41), during emergency transportation (n 5 24), to facilitate induction of general anesthesia (n 5 4) or recovery from general anesthesia (n 5 51). Additionally, the sling was used to immobilize horses with fractures (n 5 29), to reduce weight-bearing in horses with severe lameness (n 5 12), to support horses with disorders of the CNS (n 5 7), to help recumbent horses rise (n 5 9), and to provide support for horses after repair of large abdominal hernias (n 5 4). Acceptance of the ARTS by the horses was scored as excellent (n 5 153), good (n 5 19) and poor (n 5 6), and the sling was not tolerated in 3 horses. Only after longterm use (weeks) did the skin over certain pressure points become irritated, resulting in superficial pressure sores. Conclusions -The ARTS was reliable, safe, and easy to use. It proved to be ideal for a wide variety of emergencies.(J Vet Emerg Crit Care 2008; 18(6): 619-625)