A bibliographic survey was carried out on PRP and plasma gel and their derivations in PUBMED and Google Scholar to date and a clinical case study was carried out in order to provide a technical and scientific basis for the use of Plasma gel as autologous facial collagen biostimulator and clinical verification of its efficiency. After carrying out this study and analyzing the clinical results, Plasma gel and PRP used as autologous collagen biostimulator improved acne scars and skin density, a simple technique with no complications. The results were evaluated clinically, by comparative photographic analysis and patient satisfaction. It was concluded that this technique proved to be efficient and safe for facial rejuvenation.