Background: Immunization is cost-effective public health interventions strategies of the decade which under go long and careful process to ensure vaccine safeness before it reaches to the target children, it averts nearly three million mortality annually and immunization coverage is very low comparing all plans at national and regional. The aim of this systematic review and meta-analysis is to assess pooled immunization coverage in Ethiopia.Method: systematic search was done from PubMed, Google Scholar, Embase, and Hinari, SCOPUS, WHO’s Institutional Repository for Information Sharing (IRIS), African Journals Online databases, grey literature and reviewing reference lists of already identified articles. Checklist from the Joanna Briggs Institute was used to assess risk of bias of the included study while heterogeneity was assessed using I2. Funnel plot were used to assess publication bias. Meta-analysis using random effect model was used to estimate the pooled prevalence of immunization among 12-23 month children using STATA 13 software.Result: twenty eight articles were included in the meta-analysis with, a total sample size of 20,048 12-23 months children. The pooled prevalence of immunization among 12-23 month children in Ethiopia was found 47 % (95%, CI: 46.0, 47.0). Subgroup analysis by region indicated the lowest proportion of immunized children in Afar region, 21% (95%, CI: 18.0, 24.0) and the highest in Amhara region, 89% (95%, CI: 85.0, 92.0).Conclusion: Nearly 50% of 12-23 month children were fully vaccinated for this systematic review and meta-analysis but coverage is still low with clear disparity among regions. Mobile and outreach immunization sites should be planned for hard to reach area of pastoral and semi-pastoral regions. Immunization service should be integrated to private for profit and not for profit health facilities which cover 11% of health service coverage in Ethiopia.