Full immunization coverage and associated factors among children age 12-23 months in Ethiopia: systematic review and meta-analysis of observational studies

Biset, Gebeyaw; Tadesse, Abay Woday; Mihret, Setegn; Tsihay, Mekonnen

doi:10.1080/21645515.2020.1870392

Cited by 22 publications

(42 citation statements)

References 38 publications

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“…Another reason for the low utilization of immunization services was competing for priorities like income-generating activities to support their families than take their children for vaccination. These findings are similar to Babirye et al (2011) and Biset et al (2021), who have also revealed that competing priorities limited the mother's ability to complete the immunization schedule.…”

Section: Discussionsupporting

confidence: 86%

Determinants of Poor Utilization and Accessibility of Immunization Services: A Qualitative Study in Selected Counties in South Sudan

Kunjok¹,

Ajak²,

Deng³

et al. 2021

GJHS

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BACKGROUND: Reducing vaccine-preventable diseases mortality and morbidity in non-industrialized countries requires the enforcement of robust immunization strategies aimed at increasing coverage and reducing dropouts and missed immunization opportunities. Attaining high (>80%) immunization coverage with a low drop-out rate in South Sudan has been challenging because of the program’s high defaulting rates. This study aimed to determine the reasons for poor accessibility and utilization of immunization services in counties earmarked for Fragility, Emergency and Refugees (FER) in South Sudan. METHODS: A descriptive phenomenological study design was conducted across four counties of Northern Bahr El Ghazal, South Sudan, between May 2019 and December 2020 in which 42 focused group discussions and key-informant interviews involving the community and primary healthcare centers and units were conducted. Relevant EPI (Expanded program on immunization) tools were reviewed and data were analyzed using thematic analysis. RESULTS: The main reasons identified were negative attitudes towards healthcare workers and immunization services, competing priorities of the caregivers, delayed opening of the immunization sessions, insufficient cold chain facilities, inadequate knowledge and information about immunization services, and non-availability of vaccines at the health facility. CONCLUSIONS: A plan to supply adequate vaccines and related supplies to the counties by identifying stock levels in time must be a priority. Health facility micro-plan development and implementation should be supported by increased funding for the implementation of outreach and mobile sessions to reach missed children, intensified door-to-door health awareness, and regular community meetings to increase vaccine uptake.

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Section: Discussionsupporting

confidence: 86%

Determinants of Poor Utilization and Accessibility of Immunization Services: A Qualitative Study in Selected Counties in South Sudan

Kunjok¹,

Ajak²,

Deng³

et al. 2021

GJHS

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“…The total number of patients in all studies was 1,989. The reported prevalence of mortality varied from 28.6% (20) to 62.1% (21), per the included studies. The general traits of the studies that were included in the systematic review and meta-analysis were displayed in Table 1.…”

Section: Resultsmentioning

confidence: 99%

Mortality and Associated Factors Among Intensive Care Unit Admitted Adult Patients With Mechanical Ventilation in Ethiopia: A Systematic Review and Meta-Analysis

Alamaw,

Abebe,

Abate

et al. 2024

Shock

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Introduction The global demand for intensive care has risen, given its effectiveness in lowering mortality rates. Mechanical ventilation (MV) is integral to intensive care but introduces risks such as ventilator-associated complications. Ethiopia experiences a high intensive care unit (ICU) mortality rate. Objective This systematic review and meta-analysis aim to comprehensively synthesize evidence on the mortality of adults undergoing MV in Ethiopia and identify associated factors. Methods The study extensively searched databases and grey literature for research on MV outcomes, trends, and associated factors in adult ICUs. Adhering to the 2020 PRISMA checklist, a systematic review and meta-analysis sought to establish the mortality rate and key determinants among adult ICU patients on MV. The search incorporated keywords and MeSH terms, excluding studies with unsound methodologies or missing data. Data extraction, quality assessment, and analysis followed established protocols, including the JBI tool for methodological quality evaluation. STATA version 17.0 facilitated analysis, assessing heterogeneity, publication bias, and performing sensitivity and meta-regression analyses. Results The pooled mortality rate among adult ICU patients undergoing MV was 48.61% (95% CI: 40.82, 56.40%). Significant mortality-contributing factors included medical diagnosis, Glasgow Coma Scale (GCS) score, sepsis/septic shock, sedation use, multiple organ dysfunction syndrome (MODS), and cardiovascular disease. Although some pooled odds ratios seemed insignificant, closer examination revealed significant associations in individual studies. Conclusion The study underscores the urgent need for further research, improved ICU infrastructure, and healthcare personnel training in Ethiopia to enhance outcomes for mechanically ventilated patients. Identified factors offer valuable insights for targeted interventions, guiding tailored treatment strategies to reduce mortality. This study contributes to understanding mortality and associated factors in MV patients, informing initiatives to improve critical care outcomes in Ethiopia.

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“…25 Moreover, a high number of SR might lead to research waste, as the publication of overlapping SR and MA is becoming evident. 26, 27 For example, we found 28 duplicates on various topics: two on mother-to-child transmission of HIV 28, 29 , two on HIV/AIDS treatment failure 30, 31 , three on nursing process 32-34 , three on antenatal depression 35-37 , three on postnatal depression 38-40 , three on breastfeeding 41-43 , three on immunization coverage 44-46 , three on low birth weight 47-49 , two on tuberculosis treatment non-adherence 50, 51 , two on maternal-near miss 52, 53 and two on antiepleptive medication non-adherence. 54, 55 To minimize research waste, authors must register their protocol, thoroughly search protocol registration cites and communicate each other whenever possible.…”

Section: Discussionmentioning

confidence: 99%

Current status of methodological and reporting quality of systematic reviews and meta-analyses in medicine and health science fields in Ethiopia: Leveraging quantity to improve quality

Sharew

Endalamaw

Mulugeta

et al. 2022

Preprint

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IntroductionWith a rising publication rate of medicine and health sciences systematic reviews (SR) and meta-analyses (MA) in Ethiopia, there is a growing concern over their methodological and reporting quality. The aim of this study was to characterize epidemiological trends and evaluate the methodological and reporting quality of SR and MA Ethiopia.MethodsA retrospective observational overview study was conducted on medicine and health sciences SR and MA in Ethiopia that accessed through PubMed, PsycInfo, EMBASE databases and additional manual searching. SR and MA based on primary human studies associated with the Ethiopian population irrespective of the place of publication and authors’ affiliation and published until March 16, 2021 were included. Title/abstract and full-text screening were conducted in duplicate using EndNote and Covidence semiautometed reference management tools. Data extraction tool was developed by the author using PRISMA and AMSTAR-2 as a guide. We summarized background characteristics, and methodological and reporting qualities using frequencies with percentages and median with range. Two-tailed Chi-Square and Fisher’s Exact tests used for catergorical variables and Kruskal-Walis test for quantitative variables at alpha level 0.05 were used to compare the difference in background characterstics between SR and MA as well as across the publication years over time. All the analysis was done using R version 4.0.2 for macOS.ResultsOf the 3,125 total records initially identified, 349 articles (48 (13.75%) SR, and 301 (86.25%) MA) were included in our analyses. We observed a dramatic increase in publications with nearly three-quarters of SR and MA (73.9%) published after 2018. More than nine out of ten (92.8%) SR and MA included only observational studies and infectious disease, was the most researched (20.9%) subject area. Number of authors, number of affiliations, publication year, protocol registration, number of primary studies, number of references, citation counts and journal quality were significantly different between SR and MA. Both SR and MA had a low methodological and reporting quality Even though there was improvement in registering protocols, searching databases, and transparently reporting search strategy.ConclusionsThe production of SR and MA in Ethiopia has been increased over time, especially during the last three years. There is a promising trend of improvement in methodological and reporting quality even though there is much more to do. This study provide an up-to-date overview of the landscape of SR and MA publication rate and quality leverage in Ethiopia. Authors should prioritize quality over fast track publication.

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Full immunization coverage and associated factors among children age 12-23 months in Ethiopia: systematic review and meta-analysis of observational studies

Cited by 22 publications

References 38 publications

Determinants of Poor Utilization and Accessibility of Immunization Services: A Qualitative Study in Selected Counties in South Sudan

Determinants of Poor Utilization and Accessibility of Immunization Services: A Qualitative Study in Selected Counties in South Sudan

Mortality and Associated Factors Among Intensive Care Unit Admitted Adult Patients With Mechanical Ventilation in Ethiopia: A Systematic Review and Meta-Analysis

Current status of methodological and reporting quality of systematic reviews and meta-analyses in medicine and health science fields in Ethiopia: Leveraging quantity to improve quality

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