Full resolution reconstruction of whole-mount sections from digitized individual tissue fragments
Daan Schouten,
Jeroen van der Laak,
Bram van Ginneken
et al.
Abstract:Whole-mount sectioning is a technique in histopathology where a full slice of tissue, such as a transversal cross-section of a prostate specimen, is prepared on a large microscope slide without further sectioning into smaller fragments. Although this technique can offer improved correlation with pre-operative imaging and is paramount for multimodal research, it is not commonly employed due to its technical difficulty, associated cost and cumbersome integration in (digital) pathology workflows. In this work, we… Show more
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