Military aircraft are subjected to variable loads, which are the main cause of initiation and propagation of cracks in the most stressed locations of the airframe. The aim of a Full-Scale Fatigue Test (FSFT) is to represent actual load conditions in such a way that the results obtained are a good representation of the actual loads and may be used as data that give insight into the development of real fatigue damage in critical locations. The FSFT load spectrum is a generalized depiction of the expected service loads and is designed to give an overall good representation of loads exerted on the airframe’s structural elements during operation. Moreover, the discrete method of load application on the structure (exerting loads with hydraulic actuators rather than pressure fields or inertia loads expected in actual operation) may cause some local effects, which may not be present in operation. The proposed usage of direct strain data from the test include such local effects. Moreover, operational loads may vary between individual aircraft, therefore it is crucial to understand the whole process of fatigue crack onset and development in order to determine safe inspection intervals and thereby mitigate risk. This paper presents crack propagation calculations regarding the development of a crack in a critical location of the PZL-130 “Orlik” TC-II aircraft, discovered during FSFT. The discussed crack was found already developed, hence the information about nucleation and initial propagation of the crack was not available. Therefore, there was a need to recreate the whole propagation process by means of numerical estimations using the FSFT results like location of the crack and total life for model validation. Moreover, in order to gather real load data for calculations a dedicated stain gage was installed on the damaged load path to monitor the actual remote strain in the element during the FSFT. This allowed for the definition of load sequence exerted on the damaged element directly during the test rather than estimating it from the general load conditions of the wing. The calculations allowed for the estimation of crack propagation curves from initiation to critical crack length causing fatal damage. The obtained curves allowed to visualize the crack behavior due to applied load and furthermore define initial and recurring inspection intervals for the entire fleet during operation, which allowed to define which cracks could be found before they reach critical size in order to carry out mitigation actions like repair or replacement of the damaged part. The authors present the methodology for load spectrum development based on direct strain measurements and furthermore crack propagation curves estimation, validated with the actual FSFT results, which allowed to propose nondestructive inspection intervals for future operation.