Blast loads can represent a great hazard to existing structures. Their effects on structural elements can be decisive for the integrity of both the structure itself and the people within it. The behaviour of the individual elements of a building is totally different due to the heterogeneity of the materials composing them. This fact makes it necessary to carry out tests on each type of structural element in order to correctly evaluate the response of the structure. In addition, the scale effect can produce inaccurate results, making it necessary for tests to be performed on a full scale to validate the results. In this work, the results of several tests with explosives are presented, in different constructive elements, all of them carried out at full scale. These elements range from the structural elements (beams and concrete slabs) to the weak elements of a building (masonry panels).