This paper presents an experimental study on an innovative timber‐based retrofit solution for reinforced concrete (RC) framed buildings, with or without masonry infills. The intervention aims to enhance seismic resistance through a light, cost‐effective, sustainable, and reversible approach integrating energy efficiency upgrades. The method employs cross‐laminated timber (CLT) panels as infills or external retrofitting elements, mechanically connected to the RC frame through steel fasteners. The system is combined with thermal insulation for improved energy efficiency. The seismic performance of the proposed retrofit technique was assessed experimentally on a full‐scale building model at the European Laboratory for Structural Assessment (ELSA). The experiments included tests on two five‐story building configurations: a masonry‐infilled RC building as a reference and the same structure strengthened with CLT panels. Each building was subjected to unidirectional earthquake simulations of increasing intensity using the pseudodynamic (PsD) testing method with substructuring. The physical substructure of the hybrid model consisted of the first story of a two‐story mockup built and retrofitted in the laboratory, while stories two to five were simulated numerically. The paper discusses major observations from the tests, comparing the damage evolution and hysteretic responses of the two configurations. The experiments yielded promising results, showing that the suggested retrofit solution significantly increased displacement and energy dissipation capacity. The retrofitted building survived earthquake intensities up to 50% higher than the non‐retrofitted counterpart, exhibiting only slight structural damage. These pioneering experiments provide compelling data on the high effectiveness of the proposed CLT‐based retrofit system in enhancing the seismic performance of full‐scale RC buildings.
