Full-Thickness Macular Hole in Age-Related Macular Degeneration Patients With Two Distinct Entities

Rabina, Gilad; Pillar, Shani; Nemet, Achia; Levinger, Nadav; Chowers, Itay; Ehrlich, Rita; Gal-Or, Orly; Barequet, Dana; Rosenblatt, Amir; Moisseiev, Elad; Greifner, Hillel; Magal, Itay; Segal, Ori

doi:10.1097/iae.0000000000003141

Cited by 3 publications

(3 citation statements)

References 30 publications

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“…The thickness of the subfoveal choroidal layer and the retinal layer both reduced noticeably as a result of the SO tamponade [ 41 ]. According to the findings of the study conducted by Kheir WJ et al (2018), CMT levels dropped when the SO tamponade was applied, but they increased when the SO was withdrawn.…”

Section: Discussionmentioning

confidence: 99%

Retinal Nerve Fiber Layer Changes after Intraocular Silicone Oil Tamponade in Rhegmatogenous Retinal Detachment

Chikmah

Ichsan

Islam

et al. 2023

Vision

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Rhegmatogenous retinal detachment (RRD) is a serious and emergency condition that may cause visual disturbance. Treatment includes pars plana vitrectomy with a tamponade such as intraocular gas or silicone oil (SO). In many countries, silicone oil is still favorable compared to intraocular gases as tamponade for reattachment of retinal detachment surgery. The application provides a higher anatomical success rate, especially in cases of proliferative vitreoretinopathy (PVR) that were previously considered untreatable. Objective assessment of the retinal nerve fiber layer (RNFL) using optical coherence tomography (OCT) in the eye with silicone oil tamponade is a challenge because of the limitations and difficulties in taking images. This study aims to assess the RNFL thickness changes in rhegmatogenous retinal detachment patients using SO tamponade and its subsequent removal conducted on a total of 35 post-operative RRD patients. Central macular and RNFL thickness, as well as best-corrected visual acuity (BCVA), were recorded at the time of tamponade and after the removal of the SO at 1, 4, and 8 weeks, respectively. The results showed that the changes in RNFL thickness significantly decreased in the group of ≤6 months, especially in the superior and temporal quadrants, and BCVA increased after SO removal (p < 0.05). Central macular thickness was significant (p < 0.001) at the end of the visit. Improved visual acuity is associated with decreased RNFL and central macular thickness after SO removal.

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Section: Discussionmentioning

confidence: 99%

Retinal Nerve Fiber Layer Changes after Intraocular Silicone Oil Tamponade in Rhegmatogenous Retinal Detachment

Chikmah

Ichsan

Islam

et al. 2023

Vision

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“…3,4 In addition, the retina in eyes with AMD can have atrophic and degenerative changes that predispose to foveal dehiscence. 3 Most reports of MHs associated with wet AMD describe MH formation in conjunction with CNVM regression (ie, in the setting of fluid resolution after treatment with antivascular endothelial growth factor [anti-VEGF] therapy). [5][6][7][8][9] There are also many reports of MH formation during resolution of exudation in polypoidal choroidal vasculopathy treated with anti-VEGF 10 and during contraction of a treated myopic CNVM.…”

Section: Discussionmentioning

confidence: 99%

“…These aging eyes with AMD are subject to the same tractional forces that underlie typical senile MHs (eg, vitreoretinal traction during an aberrant posterior vitreous detachment [PVD] process, ERM). 3,4 In addition, the retina in eyes with AMD can have atrophic and degenerative changes that predispose to foveal dehiscence. 3 Most reports of MHs associated with wet AMD describe MH formation in conjunction with CNVM regression (ie, in the setting of fluid resolution after treatment with antivascular endothelial growth factor [anti-VEGF] therapy).…”

Section: Discussionmentioning

confidence: 99%

Full-Thickness Macular Hole Caused by Acute Subretinal Hemorrhage From Wet Age-Related Macular Degeneration

Gupta,

Lean

2023

Journal of VitreoRetinal Diseases

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Purpose: To present a case of full-thickness macular hole (MH) that developed in association with acute subretinal hemorrhage from wet age-related macular degeneration (AMD). Methods: A retrospective observational review of a single case was performed. Results: An 84-year-old man with wet AMD presented with central vision loss and floaters and was noted to have a subretinal hemorrhage and an associated MH, which subsequently progressed to MH-associated macular detachment. The patient had a pars plana vitrectomy with internal limiting membrane peeling, gas tamponade, and prone positioning, resulting in closure of the MH and improvement in visual acuity. Conclusions: A full-thickness MH developed as a result of foveal dehiscence from an acute hemorrhage caused by choroidal neovascularization in wet AMD.

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Long-term Incidence and Risk Factors of Macular Fibrosis, Macular Atrophy, and Macular Hole in Eyes with Myopic Neovascularization

Cicinelli

Franca

Felice

et al. 2022

Ophthalmology Retina

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Full-Thickness Macular Hole in Age-Related Macular Degeneration Patients With Two Distinct Entities

Cited by 3 publications

References 30 publications

Retinal Nerve Fiber Layer Changes after Intraocular Silicone Oil Tamponade in Rhegmatogenous Retinal Detachment

Retinal Nerve Fiber Layer Changes after Intraocular Silicone Oil Tamponade in Rhegmatogenous Retinal Detachment

Full-Thickness Macular Hole Caused by Acute Subretinal Hemorrhage From Wet Age-Related Macular Degeneration

Long-term Incidence and Risk Factors of Macular Fibrosis, Macular Atrophy, and Macular Hole in Eyes with Myopic Neovascularization

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