2020
DOI: 10.1038/s41598-020-76754-3
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Full wave 3D inverse scattering transmission ultrasound tomography in the presence of high contrast

Abstract: We present here a quantitative ultrasound tomographic method yielding a sub-mm resolution, quantitative 3D representation of tissue characteristics in the presence of high contrast media. This result is a generalization of previous work where high impedance contrast was not present and may provide a clinically and laboratory relevant, relatively inexpensive, high resolution imaging method for imaging in the presence of bone. This allows tumor, muscle, tendon, ligament or cartilage disease monitoring for therap… Show more

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Cited by 71 publications
(54 citation statements)
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“…The equation (5) shows that the reflection point is located at the source-receiver midpoint only when the medium is isotropic (v 1 = v 2 ) or the anisotropy symmetry axis is aligned with our coordinate system (ϕ = 0). For muscle tissue, we expect v 1 > v 2 for ϕ ∈ [−π/4, π/4), i.e., waves propagating faster along than across fiber direction [14].…”
Section: A Reflector-based Experimental Setupmentioning
confidence: 99%
“…The equation (5) shows that the reflection point is located at the source-receiver midpoint only when the medium is isotropic (v 1 = v 2 ) or the anisotropy symmetry axis is aligned with our coordinate system (ϕ = 0). For muscle tissue, we expect v 1 > v 2 for ϕ ∈ [−π/4, π/4), i.e., waves propagating faster along than across fiber direction [14].…”
Section: A Reflector-based Experimental Setupmentioning
confidence: 99%
“…We use the first transducer element as a source with a Ricker wavelet of 2 MHz center frequency and all transducers as receivers. Our approach predicts traveltimes accurately, even though the frequencies of simulated ultrasonic waves are lower than those used commercially (5)(6)(7)(8)(9)(10)(11)(12). The traveltime modelling presented here is based on the ray theory, which assumes infinite frequencies.…”
Section: Validation With Numerical Simulationsmentioning
confidence: 99%
“…Under a fluid or acoustic modeling, the effects of attenuation and shear wave propagation are not taken into account. This simplified model is often used in the imaging of soft tissues in order to reduce the complexity of the implementation, 20 but it has also been extended to targets with high impedance contrast such as bone 2123 obtaining proper quantitative estimates of the tissue characteristics. To go further, the FWI approach have been proposed as suitable method for USCT of high impedance contrast targets, and the results obtained using synthetic data are promising.…”
Section: Introductionmentioning
confidence: 99%