Fulminant Adenoid Cystic Carcinoma of the Maxillary Sinus – A Rare Finding: Case Report

Adenoid cystic carcinoma of the head and neck – treatment strategies of a highly malignant tumor with variable localizations

“…Consequently, the ACC in particular is often localized in the area of the hard palate (small salivary glands). In rare cases, ACC has also been described in other regions of the head and neck region, such as the paranasal sinuses or the tongue [ 3 , 4 ].…”

“…Typically, ACC can show increased uptake of contrast medium agent with an infiltrative spread pattern in the respective anatomical region ( Figure 1 ) [ 3 ]. However, it is difficult to clearly differentiate ACC from other malignancies of the head and neck region.…”

“…In addition, in sensitive locations with pronounced infiltration (e.g., maxillary sinus), adjuvant radiotherapy in the form of proton therapy can be helpful after surgical tumor resection [ 3 , 9 ]. Young patients in particular can benefit from this new form of radiation therapy with regard to long-term survival if they have pronounced ACC findings [ 9 ].…”

“…A two-stage surgical procedure with initial tumor resection and epithesis treatment can sometimes be advantageous in therapy planning and plastic reconstruction with the above-mentioned distant flaps after adjuvant proton therapy [ 3 ]. However, since proton therapy is only available to a limited extent, close coordination between the treating departments is essential in order to provide the patient with a state-of-the-art therapy.…”