Fulminant amebic colitis

Aristizábal, Humberto; Acevedo, J. S. Peinado; Botero, Mario Martín

doi:10.1007/bf01659055

Cited by 80 publications

(52 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…3,6,8,9 In relation to the clinical findings, the proportion of patients with tenesmus was higher among survivors. The regression model suggests tenesmus as a factor associated with a decrease risk of mortality, while low lymphocyte count had a positive association.…”

Section: Discussionmentioning

confidence: 95%

Amoebic toxic colitis: analysis of factors related to mortality

Ortiz-Castillo

Salinas-Aragón

Sánchez-Aguilar

et al. 2012

Pathogens and Global Health

View full text Add to dashboard Cite

Background: Toxic or fulminant colitis due to Entamoeba histolytica infrequently presents but is very serious. Unfortunately, there are numerous contradictory factors related to mortality. Methods: We analyzed several cases of E. histolytica infection to determine the factors related to mortality. We included patients .15 years of age who were histopathologically diagnosed with amoebic toxic colitis and treated from January 2000 through December 2006. We evaluated demographic, clinical, laboratorial, surgical, and histopathological characteristics. Results: We examined 24 patients and recorded 12 deaths (50%). Twenty patients underwent surgery within a mean time of 24 hours (range: 8-120 hours). Tenesmus and intestinal perforation were determined to be statistically significant (P,0.05) by univariate analysis. Three models of logistic regression were able to determine three statistically significant factors that affected mortality: (1) tenesmus and a lymphocyte count ,1.5610 3 cell/ml; 2) depth of invasion beyond the mucosa and a lymphocyte count ,1.5610 3 cell/ ml; 3) time spent with symptoms and perforation. Conclusions: The mortality rate determined in this study is similar to previously reported series. A low lymphocyte count, significant depth of invasion, and intestinal perforation were determined to be the factors related to increased mortality, while tenesmus and limited amount of time spent with symptoms were associated with survival. Quick diagnosis and appropriate treatment are important factors that reduce mortality.

show abstract

Section: Discussionmentioning

confidence: 95%

Amoebic toxic colitis: analysis of factors related to mortality

Ortiz-Castillo

Salinas-Aragón

Sánchez-Aguilar

et al. 2012

Pathogens and Global Health

View full text Add to dashboard Cite

show abstract

“…Typically, entamebiasis leads to a chronic course, presenting with mucus and blood in the stool. Almost all who contract E. histolytica remain carriers, and approximately 10% present with symptoms of amebic colitis, including bloody and watery diarrhea, and abdominal pain [1,2]. It is reported that about 3% of amebic colitis cases are fulminant type, leading to intestinal perforation or peritonitis [1,2].…”

Section: Discussionmentioning

confidence: 99%

“…Preoperative diagnosis of FAC is generally considered challenging, and sometimes a differential diagnosis of inflammatory or infective colitis is necessary. Because FAC is associated with high mortality [2], immediate administration of metronidazole should be considered soon after the condition is suspected or diagnosed. If FAC is suspected from clinical symptoms, and/or social history or travel history, further examination to confirm the condition is crucial.…”

Section: Discussionmentioning

confidence: 99%

A Case of Fulminant Amebic Colitis Diagnosed after Colonic Resection

Ishii¹,

Takada²

2016

J Clin Case Rep

View full text Add to dashboard Cite

Here, we report a case of fulminant amebic colitis diagnosed after colonic resection in a 66-year-old male who visited our hospital complaining of prolonged fever and consistent pain in the right abdomen. The patient had neither watery nor bloody stool. Laboratory data revealed increased white blood cell counts (15,900 cells/μl) and high levels of C-reactive protein (10.3 mg/dl). Contrast enhanced computed tomography revealed remarkably hypertrophic and edematous lesions in the right-sided colon. Stool culture revealed no pathogens. The patient was suspected to have infectious colitis; thereafter, the antibiotic flomoxef sodium (3 g/day) was administered. Colonoscopy revealed a circumferential white coat and stripped mucosal lesions in the right-sided colon; thereafter, ischemic colitis or enterohemorrhagic Escherichia coli colitis was the differential diagnosis. When the general condition of the patient and their inflammatory response deteriorated, surgical treatment was adopted. Surgical findings revealed a rightsided necrotizing colon and yellowish ascites, which was later found to contain Enterococcus faecalis and grampositive bacillus. Pathological findings revealed the presence of trophozoites of Entamoeba histolytica. Consequently, fulminant amebic colitis was diagnosed. The postoperative course was uneventful, and the patient was discharged on postoperative day 18.

show abstract

“…In each report, delay in the diagnosis of amebiasis was associated with poor prognosis, because it is challenging to establish a prompt diagnosis in most situations. Moreover, high mortality after bowel resection in amebic colitis results from difficulties in placing the sutures due to the vulnerability of the intestinal wall (13).…”

Section: Discussionmentioning

confidence: 99%

Fulminant Amebic Colitis in an HIV-infected Homosexual Man

2011

View full text Add to dashboard Cite

We present a case of fulminant amebic colitis in a human immunodeficiency virus (HIV)-infected homosexual man. The patient developed colonic perforation over a short time despite empirical therapy with metronidazole, and underwent right hemicolectomy. Amebic colitis was pathologically diagnosed by identifying invasive trophozoites of Entamoeba in a surgical specimen. Amebic colitis is one of the important differential diagnoses of acute abdomen in HIV-infected patients and/or homosexual men, especially in East Asia. Although fulminant amebic colitis is a rare manifestation of amebiasis, early diagnosis and treatment are thought to be important to improve the outcome of this highly fatal complication.

show abstract

Fulminant amebic colitis

Cited by 80 publications

References 14 publications

Amoebic toxic colitis: analysis of factors related to mortality

Amoebic toxic colitis: analysis of factors related to mortality

A Case of Fulminant Amebic Colitis Diagnosed after Colonic Resection

Fulminant Amebic Colitis in an HIV-infected Homosexual Man

Contact Info

Product

Resources

About