Fulminant Dermatomyositis after Removal of a Cancer

Abraham, Zeev; Rozenbaum, Michael; Glück, Zahava; Feuerman, Eleasar J.

doi:10.1111/j.1346-8138.1992.tb03253.x

Cited by 2 publications

(1 citation statement)

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“…We encountered a case of DM that developed immediately after breast cancer surgery in a patient with a history of severe drug eruption during neoadjuvant chemotherapy. The development of DM after the diagnosis of malignancy is relatively uncommon ( 15 , 16 ), and the development of DM after the surgical treatment of breast cancer has only been reported once previously, in a case of primary limited systemic sclerosis [calcinosis, Raynaud phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasis (CREST) syndrome] ( 17 ). The clinical course of DM is usually correlated with the course of the underlying malignancy ( 16 , 18 , 19 ).…”

Section: Discussionmentioning

confidence: 99%

Occurrence of Dermatomyositis Immediately after Mastectomy Subsequent to Severe Chemotherapeutic Drug Eruption

et al. 2017

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We herein report a patient with breast cancer who developed dermatomyositis (DM) immediately after mastectomy. She had a history of severe drug eruption during neoadjuvant chemotherapy six months previously. Within a month after the operation, myalgia and rash, including Gottron's papules, developed, and skeletal-muscle enzymes elevated, so she was diagnosed with probable DM according to the Bohan and Peter criteria. In many neoplastic DM cases, the course of the disease parallels the course of the malignancy. Possible mechanisms were suggested to explain the development of DM in the present case and offer new insight into autoimmune diseases.

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