Fulminant Type 1 diabetes mellitus associated with acute hepatitis A

Abstract

solution or sliding-scale subcutaneous administrations. CSII can improve glycaemia safely as well as quality of life in patients on TPN [12,16]. Formal guidelines in this area remain limited. Acknowledging the absence of clinical trials testing the effect of glycaemic control on outcomes in patients on TPN, CSII is an option for glycaemic control.We suggest that clinicians consider the possibility of primary adrenal insufficiency and other endocrine gland involvement in patients with Gardner's syndrome. As there are no guidelines to guide therapy with CSII in this setting, clinical trials are needed that compare insulin regimes or glycaemic targets with respect to clinical outcomes. In the meantime, CSII provides an option for glycaemic control in complex TPN-dependent patients.

Fulminant Type 1 Diabetes Mellitus Associated with Coxsackie Virus Type A2 Infection: A Case Report and Literature Review

“…Our patient presented with fever and fatigue without any other symptoms before developing FT1D, and the Coxsackie A2 virus infection was confirmed serologically. Table 2 summarizes the reported cases in which virus infection was proven to be involved in the development of FT 1D (7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21). These cases include adults of both sexes.…”

“…These cases include adults of both sexes. All of the patients were Japanese, except for case 18, who was Korean (17). Some of the patients had the class II HLA DRB1*04:05-DQB1*04:01 or DRB1*09:01-DQB1*03:03 haplotype, which increase the susceptibility of Japanese individuals to FT1D (24).…”

A Rare Association of Hepatitis a Virus Infection with Type-1 Diabetes

“… 4 The association of HAV Infection with type-1 diabetes have been described in adult. 5-8 To the best of our knowledge, our case is the first case report in a children. Although the pathogenesis of type-1 diabetes is unknown, viral infections may or may not be involved.…”

“…Hwang and colleagues 5 reported an adult man who presented with fulminant type-1 diabetes and acute HAV. Our child did not develop complications of diabetes, and HAV recovered spontaneously.…”

Fulminant type 1 diabetes occurring in a child in association with acute hepatitis A infection: case report and review of literature

“…Makeen AM reported three patients who developed diabetes mellitus and presented with diabetic ketoacidosis within weeks of acute hepatitis A infection [11]. Another report of fulminant type 1 DM associated with acute hepatitis A was published from Korea [12].…”