2011
DOI: 10.5897/ajb10.1497
|View full text |Cite
|
Sign up to set email alerts
|

Fumaric acid, an antibacterial component of Aloe vera L.

Abstract: The acetoacetate fraction partitioned from Aloe vera L. showed an effective antibacterial activity against four clinically frequent pathogenic bacteria. Through a series of chromatographic methods and activity assays, one compound was obtained and it has potent antibacterial activity. Based on the data of mass spectrometry, 1 H-NMR, 13C-NMR and IR spectra, this compound was determined to be fumaric acid. This study concluded that fumaric acid is one of the antibacterial components in A. vera.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1

Citation Types

0
2
0

Year Published

2014
2014
2022
2022

Publication Types

Select...
5
1

Relationship

0
6

Authors

Journals

citations
Cited by 25 publications
(2 citation statements)
references
References 29 publications
0
2
0
Order By: Relevance
“…In comparison, the highest contents were those of fumaric acid (822.2 mg/100 g), citric acid (646.5 mg/100 g), and malic acid (211.5 mg/100 g). Fumaric acid, and its esters, possess the following: anti‐inflammatory, hepatoprotective, analgesic, antitumor, and anti‐intoxication activities, as well as strong antibacterial activity against Staphylococcus aureus, Streptococcus , Escherichia coli , and Salmonella (He et al., 2011 ; Shakya et al., 2014 ).…”
Section: Resultsmentioning
confidence: 99%
“…In comparison, the highest contents were those of fumaric acid (822.2 mg/100 g), citric acid (646.5 mg/100 g), and malic acid (211.5 mg/100 g). Fumaric acid, and its esters, possess the following: anti‐inflammatory, hepatoprotective, analgesic, antitumor, and anti‐intoxication activities, as well as strong antibacterial activity against Staphylococcus aureus, Streptococcus , Escherichia coli , and Salmonella (He et al., 2011 ; Shakya et al., 2014 ).…”
Section: Resultsmentioning
confidence: 99%
“…(SCAN, 2003). Fumaric acid and its esters possess anti-inflammatory, hepatoprotective, analgesic (Shakya et al 2014), antitumor and anti-intoxication activities (Kuroda et al 1981), as well as strong antibacterial activity against Staphylococcus aureus and Streptococcus, Escherichia coli and Salmonella (He et al 2011). The esters of fumaric acid (especially, dimethyl fumarate) have been used in the biomedical treatment of psoriasis, multiple sclerosis and granuloma annulare (Schweckendiek 1959;Kreuter et al 2002;Moharregh-Khiabaniet et al 2009;Das et al 2016).The cultivation of plant cells and tissue cultures is well known prospective technology for production of valuable biologically active substances (Steingroewer et al 2013).…”
Section: Introductionmentioning
confidence: 99%