Fumonisins in foods from Cordoba (Argentina), presence and genotoxicity

Lerda, Daniel; Bistoni, M. Biaggi; Peralta, N.; Ychari, S.; Vázquez, María Mercedes Vázquez; Bosio, G.

doi:10.1016/j.fct.2004.12.019

Cited by 53 publications

(40 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…They have suggested that blood is a valuable tissue for monitoring the genotoxicity of AFB 1 . Virtually, blood offers several advantages as a test system (Lerda et al 2005). The first is easy availability of large numbers of human blood cells.…”

Section: Introductionmentioning

confidence: 99%

Boric acid: a potential chemoprotective agent against aflatoxin b1 toxicity in human blood

Türkez

Geyikoğlu

2010

Cytotechnology

View full text Add to dashboard Cite

Aflatoxin B 1 is the most potent pulmonary and hepatic carcinogen. Since the eradication of Aflatoxin B 1 contamination in agricultural products has been difficult, the use of natural or synthetic free radical scavengers could be a potential chemopreventive strategy. Boric acid is the major component of industry and its antioxidant role has recently been reported. The present study assessed, for the first time, the effectiveness of boric acid following exposure to Aflatoxin B 1 on human whole blood cultures. The biochemical characterizations of glutathione and some enzymes have been carried out in erythrocytes. Alterations in malondialdehyde level were determined as an index of oxidative stress. The sister-chromatid exchange and micronucleus tests were performed to assess DNA damages in lymphocytes. Aflatoxin B 1 treatment significantly reduced the activities of antioxidants by increasing malondialdehyde level (30.53 and 51.43%) of blood, whereas, the boric acid led to an increased resistance of DNA to oxidative damage induced by Aflatoxin B 1 in comparison with control values (P \ 0.05). In conclusion, the support of boric acid was especially useful in Aflatoxin-toxicated blood. Thus the risk on tissue targeting of Aflatoxin B 1 could be reduced ensuring early recovery from its toxicity.

show abstract

Section: Introductionmentioning

confidence: 99%

Boric acid: a potential chemoprotective agent against aflatoxin b1 toxicity in human blood

Türkez

Geyikoğlu

2010

Cytotechnology

View full text Add to dashboard Cite

show abstract

“…Besides they have been associated with human oesophageal cancer in the Transkei region of South Africa and China, and with neural tube defects (NTD) in South Texas, USA (Lino et al, 2004(Lino et al, , 2006Lerda et al, 2005;Shephard et al, 1996;Stack, 1998). On the basis of toxicological evidence, the International Agency for Research on Cancer (IARC) classified FB 1 as a possible carcinogen to humans, Group 2B (IARC, 2002).…”

Section: Introductionmentioning

confidence: 99%

Occurrence of fumonisins B1 and B2 in broa, typical Portuguese maize bread

Lino

Silva

Pena

et al. 2007

International Journal of Food Microbiology

View full text Add to dashboard Cite

Fumonisin B 1 (FB 1 ) and fumonisin B 2 (FB 2 ) are mycotoxins mainly produced by Fusarium verticillioides, and Fusarium proliferatum, fungi species most commonly isolated from maize. The natural occurrence of FB 1 and FB 2 in broa, typical Portuguese maize bread, was evaluated in 30 samples. Twenty five were found positive with levels ranging from 142 to 550 μg kg − 1 . The limit established by the European regulations was exceeded by 27% of the samples. The tolerable daily intake for fumonisin B 1 , and B 2 , alone or in combination, for all of the analysed samples, was lower than 2 μg kg − 1 body weight per day established by the European Commission.

show abstract

“…Temperature, storage time and degree of fungal contamination prior to storage, insect and mite activity facilitate fungi dissemination [8]. There is a general increase in consumption of contaminated grain with mycotoxins which causes different health problems including death [14,15]. The rank of fungi is second after insects as the cause of deterioration and loss of maize [16].…”

Section: Introductionmentioning

confidence: 99%

Detection of Fungi Infecting Maize (Zea mays L.) Seeds in Different Storages Around Jimma, Southwestern Ethiopia

Tsedaley¹,

Adugna²

2016

J Plant Pathol Microbiol

View full text Add to dashboard Cite

Maize is attacked by more than sixty diseases and a number of species of insect pests in the field as well as in the storage. Fungi are among the principal causes of deterioration and yield loss on farmers' maize during the storage period. Among the storage fungal pathogens Aspergillus, Fusarium and Penicillium are the most predominant species attacking maize seed and resulting in reduction in seed germination. The study was conducted at the Jimma University College of Agriculture and Veterinary Medicine in plant pathology laboratory. Three maize varieties and two levels of disinfection were used and arranged in complete block design with five replications. The highest frequency of Aspregilus spp. (40.4%) at farmer preserved seed with surface disinfected kernels on agar plate were recorded. The highest relative density of Fusarium spp. (51%) was only recorded on agar plate test from the farmer preserved seed without. The lowest germination percentage (62%) were recorded on the farmer preserved seed which was not disinfected. The Aspregilus spp. are the most dominant fungi followed by Fusarium spp. isolated in this study as well as in Ethiopia. These fungi are important in producing secondary metabolites which are carcinogenic to both humans and animals.

show abstract

Fumonisins in foods from Cordoba (Argentina), presence and genotoxicity

Cited by 53 publications

References 24 publications

Boric acid: a potential chemoprotective agent against aflatoxin b1 toxicity in human blood

Boric acid: a potential chemoprotective agent against aflatoxin b1 toxicity in human blood

Occurrence of fumonisins B1 and B2 in broa, typical Portuguese maize bread

Detection of Fungi Infecting Maize (Zea mays L.) Seeds in Different Storages Around Jimma, Southwestern Ethiopia

Contact Info

Product

Resources

About