Functional Advantage After Radical Segmentectomy Versus Lobectomy for Lung Cancer

Harada, Hiroaki; Okada, Morihito; Sakurai, Toshihiko; Matsuoka, Hidehito; Tsubota, Noriaki

doi:10.1016/j.athoracsur.2005.06.010

Cited by 271 publications

(210 citation statements)

References 11 publications

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“…A few studies have reported good survival after limited resection of peripheral early stage lung cancers, and some have even stated that long-term survival after limited resection was equivalent to that after lobectomy (21,61). In addition, limited resection preserved more lung function postoperatively than did lobectomy (62). This is important in that limited resection would offer patients a higher tolerance for the second lung resection, given that as many as 11.5% of patients who undergo resection of lung cancer develop additional primary lung cancers within their lifetimes (60).…”

Section: Surgical Approach For Subsolid Nodulesmentioning

confidence: 99%

Pulmonary subsolid nodules: what radiologists need to know about the imaging features and management strategy

Kim¹,

Park²,

Koh³

et al. 2013

Diagn Interv Radiol

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Section: Surgical Approach For Subsolid Nodulesmentioning

confidence: 99%

Pulmonary subsolid nodules: what radiologists need to know about the imaging features and management strategy

Kim¹,

Park²,

Koh³

et al. 2013

Diagn Interv Radiol

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“…The study of HARADA et al [46] was also conducted in patients who could tolerate a lobectomy, but who were assigned to radical segmentectomy (38 patients) or lobectomy (45 patients) in a nonrandomised way after the patients had given their consent. In this study, FVC, FEV1 and anaerobic threshold were measured pre-operatively and at 2 and 6 months after the operation.…”

Section: Post-operative Pulmonary Functionmentioning

confidence: 99%

“…These two studies [45,46] were performed in patients with good pre-operative pulmonary function. In patients with lung disease, careful evaluation of the type, degree and location of the lung abnormalities is important in order to select the best lung resection.…”

Section: Post-operative Pulmonary Functionmentioning

confidence: 99%

Sublobar resection for lung cancer

Rami–Porta

Tsuboi²

2009

Eur Respir J

102

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Sublobar resection for small lung cancers has been debated frequently and is still a controversial issue. The only randomised trial comparing lobectomy with sublobar resections found a significantly higher recurrence rate for the latter, but failed to show significant differences in survival, although survival was better for the lobectomy group. One meta-analysis and several nonrandomised comparisons have confirmed these results. In general, lobectomy and sublobar resections have similar 5-yr survival rates. Local recurrence after wedge resection is higher than after segmentectomy. However, for patients aged .71 yrs, lobectomy and wedge resection are associated with similar survival. For tumours of f2 cm, segmentectomy is equivalent to lobectomy, but survival after segmentectomy is worse if performed for larger tumours. For both segmentectomy and wedge resection, tumour margins should be o1 cm wide to avoid recurrence. For pure bronchioloalveolar carcinoma of f2 cm, diagnosed intraoperatively with certainty, sublobar resection seems equivalent to lobectomy, and because there is no nodal involvement, systematic nodal dissection may not be necessary. In case of doubt, however, lobectomy with systematic nodal dissection will ensure complete resection and adequate staging. More randomised trials are needed to confirm all these issues.

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“…This is because ''more'' surgery (ie, lobectomy) results in worse pulmonary function compared with ''less'' surgery. [14][15][16] However, the risk of local recurrence is greater with surgeries that are less extensive than a lobectomy. 3 There is substantial variation in the reported rate of local recurrence for patients with stage I disease (range, 6%-45%).…”

Section: Discussionmentioning

confidence: 99%

Limited resection followed by intraoperative seed implantation is comparable to stereotactic body radiotherapy for solitary lung cancer

Parashar¹,

Patel²,

Monni³

et al. 2010

Cancer

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BACKGROUND:The objective of this study was to compare the outcomes of patients who underwent wedge resection plus intraoperative brachytherapy versus patients who received stereotactic body radiotherapy (SBRT) for single malignant lung nodules. METHODS: A retrospective chart review included 55 patients who were treated for single lung nodules, and 47 of those patients who had adequate information were chosen for the current analysis. Twentyfive patients with single malignant lung nodules received SBRT. Twenty-two patients underwent limited surgical resection plus radioactive seed implantation for solitary malignant lung nodules. RESULTS: Univariate statistical analysis demonstrated a significance difference only for age in the 2 groups: The mean age in the radioactive seed group (66.6 years) was statistically significantly different from the mean of the age in the SBRT group (75.9 years; 2-sided P ¼ .04). No significant differences were observed between the 2 groups in terms of local control, distant metastasis, survival, or toxicity. CONCLUSIONS: The current results demonstrated comparable efficacy in outcome and toxicity between surgical resection with radioactive seed implantation and SBRT for the treatment of single malignant lung nodules in patients who were not candidates for lobectomy/pneumonectomy. Cancer 2010;116:5047-53.

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Functional Advantage After Radical Segmentectomy Versus Lobectomy for Lung Cancer

Cited by 271 publications

References 11 publications

Pulmonary subsolid nodules: what radiologists need to know about the imaging features and management strategy

Pulmonary subsolid nodules: what radiologists need to know about the imaging features and management strategy

Sublobar resection for lung cancer

Limited resection followed by intraoperative seed implantation is comparable to stereotactic body radiotherapy for solitary lung cancer

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