Functional and Cognitive Recovery of Patients With Traumatic Brain Injury

Oh, HyunSoo; Seo, WhaSook

doi:10.4037/ccn2009279

Cited by 8 publications

(11 citation statements)

References 27 publications

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“…The patients' clinical findings were collected from their hospital records. According to the clinical literature [16], 24 attributes affecting Glasgow Outcome Scale (GOS) of patients were considered as input attributes. The following attributes were collected during their hospitalization in ICU: age, gender, CT scan findings, pulse rate, respiratory rate, pupil's size, reactivity, and the cause of injury.…”

Section: Datasetmentioning

confidence: 99%

“…In medicine, one of the most sensitive and complex situations requiring rapid, decisive, and correct decision-making is measuring the consciousness in TBI patients [16]. Globally, TBI is an important cause of death in people under 45 years of age, and 50 % of all deaths in the same age group stem from head trauma [17].…”

Section: Introductionmentioning

confidence: 99%

“…Lingsma et al contended that prognostic predictions are extremely difficult to make in TBI patients, but many variables are found to be important in this outcome [18]. In addition to the abovementioned study, recent studies on this subject consisted of Glasgow Coma Scale (GCS) only [19], RAIN [20], and others [16,[21][22][23][24][25][26][27][28][29][30]. They are different in methodology, objectives, study design, and definition of the outcome.…”

Section: Introductionmentioning

confidence: 99%

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Identifying Important Attributes for Prognostic Prediction in Traumatic Brain Injury Patients

Pourahmad¹,

Hafizi-Rastani²,

Khalili³

et al. 2016

Methods Inf Med

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Section: Datasetmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Identifying Important Attributes for Prognostic Prediction in Traumatic Brain Injury Patients

Pourahmad¹,

Hafizi-Rastani²,

Khalili³

et al. 2016

Methods Inf Med

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“…Here, endogenous factors, such as metabolic, cellular, cytotoxic, and vasogenic edema, and biochemical derangements as well as exogenous factors, such as hypoxia and hypotension, lead to neuronal cell degeneration and, ultimately, neuronal death (Kochanek et al, 2000). The goal in the acute injury phase is to improve cerebral perfusion and to stabilize the injured brain while promoting neuroprotection strategies to optimize functional outcomes (Anderson, Brown, & Newitt, 2010; Coronado, et al, 2011; Langlois, Rutland-Brown, & Thomas, 2004; Oh & Seo, 2009; Faul, Xu, Wald, & Coronado, 2010). This acute phase may occur for days to weeks in the injured brain, and it is within this time frame that the majority of the biomarker study research has occurred, because associating a biomarker with cascading protein activity may lead to identifying outcomes (Papa et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

State of the Science of Pediatric Traumatic Brain Injury: Biomarkers and Gene Association Studies

Reuter‐Rice¹,

Eads²,

Berndt³

et al. 2015

Annu Rev Nurs Res

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Objectives Our objective is to review the most widely used biomarkers and gene studies reported in pediatric traumatic brain injury (TBI) literature, to describe their findings, and to discuss the discoveries and gaps that advance the understanding of brain injury and its associated outcomes. Ultimately, we aim to inform the science for future research priorities. Data sources We searched PubMed, MEDLINE, CINAHL, and the Cochrane Database of Systematic Reviews for published English language studies conducted in the last 10 years to identify reviews and completed studies of biomarkers and gene associations in pediatric TBI. Of the 131 biomarker articles, only 16 were specific to pediatric TBI patients, whereas of the gene association studies in children with TBI, only four were included in this review. Conclusion Biomarker and gene attributes are grossly understudied in pediatric TBI in comparison to adults. Although recent advances recognize the importance of biomarkers in the study of brain injury, the limited number of studies and genomic associations in the injured brain has shown the need for common data elements, larger sample sizes, heterogeneity, and common collection methods that allow for greater understanding of the injured pediatric brain. By building on to the consortium of interprofessional scientists, continued research priorities would lead to improved outcome prediction and treatment strategies for children who experience a TBI. Implications for nursing research Understanding recent advances in biomarker and genomic studies in pediatric TBI is important because these advances may guide future research, collaborations, and interventions. It is also important to ensure that nursing is a part of this evolving science to promote improved outcomes in children with TBIs.

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“…4 The extent of their injuries can render patients who have severe TBI without legal capacity or the ability to provide informed consent or refuse medical treatment. 4 The extent of their injuries can render patients who have severe TBI without legal capacity or the ability to provide informed consent or refuse medical treatment.…”

mentioning

confidence: 99%

Surrogate Decision Making for Patients With Severe Traumatic Brain Injury

Long

Clark

Cook

2011

Journal of Trauma Nursing

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Each year more than 1.7 million people experience traumatic brain injury. This qualitative descriptive study sought to describe how surrogate decision makers for patients with severe traumatic brain injury made the decision to withdraw or continue life support, and whether they believed that the health care team could have been of greater assistance. Six of 10 surrogates elected to withdraw life-sustaining treatment. Eight surrogates said that they would make the same proxy decisions if they had to do it again. Surrogates used multiple inputs to make treatment decisions and described the need for support from a trauma advanced practice nurse or palliative care team.

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Functional and Cognitive Recovery of Patients With Traumatic Brain Injury

Cited by 8 publications

References 27 publications

Identifying Important Attributes for Prognostic Prediction in Traumatic Brain Injury Patients

Identifying Important Attributes for Prognostic Prediction in Traumatic Brain Injury Patients

State of the Science of Pediatric Traumatic Brain Injury: Biomarkers and Gene Association Studies

Surrogate Decision Making for Patients With Severe Traumatic Brain Injury

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