Functional assessment of high‐grade ICA stenosis with duplex ultrasound and transcranial Doppler

Zachrisson, Helene; Fouladiun, Marita; Blomstrand, Christian; Holm, Jan; Volkmann, Reinhard

doi:10.1111/j.1475-097x.2011.01118.x

Cited by 14 publications

(17 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The role of TCD and transcranial color‐coded duplex (TCCD) in understanding the flow dynamics following an acute ischemic stroke is evolving . In this review, we highlighted the role of TCD and TCCD in detecting CF following an acute ischemic stroke.…”

Section: Introductionmentioning

confidence: 99%

Transcranial Doppler and Transcranial Color Duplex in Defining Collateral Cerebral Blood Flow

Saqqur

Khan

Derksen

et al. 2018

Journal of Neuroimaging

View full text Add to dashboard Cite

In an acute stroke setting, transcranial Doppler (TCD) and transcranial color-coded duplex (TCCD) have an important diagnostic utility in the monitoring of an arterial occlusion and microemboli detection. In addition, TCD has proven to be a very useful tool in the detection and progression of cerebral vasospasm in patients with subarachnoid hemorrhage. TCD/TCCD may have an important role in defining collateral blood flow (CF) in stroke patients. It is a noninvasive technique and can be utilized repeatedly allowing for changes in the blood flow dynamics as treatment is delivered. In this review, we outlined the evolving role of TCD/TCCD in defining CF in patients with an acute ischemic stroke, predicting clinical outcome and monitoring the treatment's efficacy of the CF augmentation.

show abstract

Section: Introductionmentioning

confidence: 99%

Transcranial Doppler and Transcranial Color Duplex in Defining Collateral Cerebral Blood Flow

Saqqur

Khan

Derksen

et al. 2018

Journal of Neuroimaging

View full text Add to dashboard Cite

show abstract

“…A common cause of ischemic stroke is insufficient blood supply from the internal carotid artery (ICA) to one side of the brain. Currently, vascular imaging techniques are available for evaluation of ICA stenosis and blood velocity in subjects with ischemic stroke (Bleeker et al, 2012; Gough, 2011; Marquering et al, 2012; Rodriguez et al, 2011; Zachrisson et al, 2012). Since oxygenated blood is supplied to the eye and brain by the ICA, assessment of the ocular microcirculation may provide useful information about the cerebral blood supply.…”

Section: Introductionmentioning

confidence: 99%

Feasibility of assessment of conjunctival microvascular hemodynamics in unilateral ischemic stroke

Valeshabad

Wanek

Mukarram

et al. 2015

Microvascular Research

View full text Add to dashboard Cite

Since the internal carotid artery supplies blood to both the eye and the brain, ocular microvascular hemodynamics can be altered due to ischemic stroke. The purpose of the current study was to establish the feasibility of conjunctival microcirculation imaging for detection of inter-ocular differences in microvascular hemodynamics in subjects with unilateral ischemic stroke. Conjunctival microcirculation imaging was performed in both eyes of 15 healthy control subjects and 12 subjects following unilateral ischemic stroke. Diameter and axial blood velocity were measured in multiple conjunctival venules of each eye. A two-way repeated measures analysis of variance was performed to determine the effects of stroke (control vs. stroke) and side of stroke (ipsilateral vs. contralateral) on conjunctival diameter and axial blood velocity. There was not a significant main effect of stroke on conjunctival diameter (P = 0.7) or conjunctival axial blood velocity (P = 0.9). There was not a significant main effect of side of stroke on conjunctival diameter (P = 0.8), but there was a significant main effect of side of stroke on conjunctival axial blood velocity (P = 0.02). There was a significant interaction effect between stroke and side of stroke (P = 0.04), indicating conjunctival axial blood velocity was lower in ipsilateral eyes than in contralateral eyes of stroke subjects. Conjunctival axial blood velocity and internal carotid artery blood velocity were correlated in stroke subjects (r = 0.75, P = 0.01, N = 10). Conjunctival microcirculation imaging is a feasible method to detect inter-ocular differences in microvascular hemodynamics in subjects with unilateral ischemic stroke.

show abstract

“…A high back pressure may diminish forward flow and thus the maximal flow velocity may decrease [22,23]. The presence of marked collateral circulation from for example SMA through the gastroduodenal arcade to CA, thus could diminish flow velocities in CA and therefore a high grade CA stenosis could be difficult to detect using flow velocity criteria [16,24]. In addition major calcifications may corrupt both the image and flow detection.…”

Section: Discussionmentioning

confidence: 99%

Postprandial Evaluation of Possible Collateral Pathways in Chronic Mesenteric Ischemia with Duplex Ultrasound

Zachrisson¹

2014

J Med Diagn Meth

View full text Add to dashboard Cite

Objective: Duplex scanning may be used to detect high-grade stenoses in the mesenteric vessels in patients with suspect Chronic Mesenterial Ischemia (CMI). The aim of the study was to evaluate reserve and collateral vascular function in relation to bowel symptoms in patients with CMI. Methods:Fourteen consecutive patients, referred to the vascular laboratory with suspicion of CMI, 7 men (average 79 years), and 7 women (average 66 years), were investigated by Duplex ultrasound (DUS) of the visceral arteries. All patients were examined both fasting and 30 min after a standard meal. A reference group of 10 patients with diffuse bowel symptoms (5 men and 5 women, (average 75 years) were investigated by the same DUS protocol, all showing normal mesenteric arteries. Possible collateral reserve capacity was defined as a marked increase of flow velocities (>20%) in vessels with lesions and/or in non-affected vessels.Results: All patients had a significant stenosis (>70%) in one or several visceral arteries at the baseline DUS investigation. Six patients had abdominal pain after the test meal, whilst 8 patients experienced no pain. In patients without postprandial pain a possible collateral reserve capacity was detected. In this group superior mesenteric artery (SMA) peak systolic velocity (PSV) increased significantly (baseline PSV 2.6 ± 1.3 m/s vs. postprandial PSV 4.1 ± 1.6 m/s, P < 0.05) whereas patients with postprandial pain showed no signs of collateral reserve capacity in any vessel except one patient who showed possible collateral reserve in one vessel. In the reference group a significant increase of PSV was seen in SMA only, (1.7 ± 0.6, vs. 2.5 ± 0.9, P < 0.05). Conclusion:Postprandial duplex adds information about the functional flow limitation of the stenosis and possible collateral reserve flow capacity. Further studies have to be performed to establish criteria for selection of patients appropriate for intervention.

show abstract

Functional assessment of high‐grade ICA stenosis with duplex ultrasound and transcranial Doppler

Cited by 14 publications

References 25 publications

Transcranial Doppler and Transcranial Color Duplex in Defining Collateral Cerebral Blood Flow

Transcranial Doppler and Transcranial Color Duplex in Defining Collateral Cerebral Blood Flow

Feasibility of assessment of conjunctival microvascular hemodynamics in unilateral ischemic stroke

Postprandial Evaluation of Possible Collateral Pathways in Chronic Mesenteric Ischemia with Duplex Ultrasound

Contact Info

Product

Resources

About