Functional brain asymmetry, handedness and menarcheal age

Nikolova, Piareta; Stoyanov, Zlatislav; Negrev, Negrin

doi:10.1016/0167-8760(94)90007-8

Cited by 14 publications

(4 citation statements)

References 13 publications

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“…Previous literature has demonstrated the impact of sex hormones on the development of cerebral lateralization (e.g., Diamond, 1991), and pubertal timing has been related to functional asymmetry (Nikolova et al, 1994). Similarly, in this study, right parietal maturation appears linked to pubertal stage whereas left parietal development is not, suggesting asymmetrical cortical development that may be hormonally influenced.…”

Section: Fmri Response and Agesupporting

confidence: 66%

fMRI reveals alteration of spatial working memory networks across adolescence

Schweinsburg

Nagel

Tapert

2005

J. Inter. Neuropsych. Soc.

104

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Recent studies have described neuromaturation and cognitive development across the lifespan, yet few neuroimaging studies have investigated task-related alterations in brain activity during adolescence. We used functional magnetic resonance imaging (fMRI) to examine brain response to a spatial working memory (SWM) task in 49 typically developing adolescents (25 females and 24 males; ages 12−17). No gender or age differences were found for task performance during SWM. However, age was positively associated with SWM brain response in left prefrontal and bilateral inferior posterior parietal regions. Age was negatively associated with SWM activation in bilateral superior parietal cortex. Gender was significantly associated with SWM response; females demonstrated diminished anterior cingulate activation and males demonstrated greater response in frontopolar cortex than females. Our findings indicate that the frontal and parietal neural networks involved in spatial working memory change over the adolescent age range and are further influenced by gender. These changes may represent evolving mnemonic strategies subserved by ongoing adolescent brain development.

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Section: Fmri Response and Agesupporting

confidence: 66%

fMRI reveals alteration of spatial working memory networks across adolescence

Schweinsburg

Nagel

Tapert

2005

J. Inter. Neuropsych. Soc.

104

View full text Add to dashboard Cite

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“…There are two supporting facts in this context: (a) it is known that interleukin-1β (IL-1β) can stimulate the HPA axis to increase the plasma levels of corticosterone, and (b) the cortical regulation of cortisol secretion is under the primary control of the right hemisphere [5,15]. Our previous investigations (although on different physiological functions) also provided evidence that hypothalamic-pituitary-glandular axes operate in a dependent relationship with individual differences in brain asymmetry [23,24]. Hori et al [25] focused their attention on the roles and mechanisms of neural communication between the brain and the immune system, and summarized: (a) primary and secondary lymphoid organs are sympathetically innervated; (b) different types of immunocompetent cells possess alpha-and beta-adrenergic receptors; (c) the exposure of lymphocytes and macrophages to adrenergic agonists in vitro modulates their functions; (d) a surgical or chemical sympathectomy alters the immune responses in rodents; (e) the altered activities of the splenic sympathetic nerves is causally related to the alteration in immunological responses (for instance NK cytotoxicity).…”

Section: Brain-immune System Interactionsmentioning

confidence: 95%

Brain asymmetry, immunity, handedness

et al. 2011

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AbstractThe principle of symmetry-asymmetry is widely presented in the structural and functional organization of the nonliving and living nature. One of the most complex manifestations of this principle is the left-right asymmetry of the human brain. The present review summarizes previous and contemporary literary data regarding the role of brain asymmetry in neuroimmunomodulation. Some handedness-related peculiarities are outlined additionally. Brain asymmetry is considered to be imprinted in the formation and regulation of the individual’s responses and relationships at an immunological level with the external and internal environment. The assumptions that the hemispheres modulate immune response in an asymmetric manner have been confirmed in experiments on animals. Some authors assume that the right hemisphere plays an indirect role in neuroimmunomodulation, controlling and suppressing the left hemispheric inductive signals.

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“…Thus, a connection between handedness and the appearance of sexual maturity in women has been described. In left-handed women, menarche appeared earlier than in right-handed women [20]. Furthermore, Jones and colleagues [21] had shown that the content of various neurotransmitters in the lizard brain predominated on the ipsilateral side to that of the ovary in which ovulation was occurring.…”

Section: The Early Developmentmentioning

confidence: 99%

Brain Asymmetry: Towards an Asymmetrical Neurovisceral Integration

et al. 2021

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Despite the ancestral evidence of an asymmetry in motor predominance, going through the inspiring discoveries of Broca and Wernicke on the localization of language processing, continuing with the subsequent noise coinciding with the study of brain function in commissurotomized patients—and the subsequent avalanche of data on the asymmetric distribution of multiple types of neurotransmitters in physiological and pathological conditions—even today, the functional significance of brain asymmetry is still unknown. Currently, multiple evidence suggests that functional asymmetries must have a neurochemical substrate and that brain asymmetry is not a static concept but rather a dynamic one, with intra- and inter-hemispheric interactions between its various processes, and that it is modifiable depending on changing endogenous and environmental conditions. Furthermore, based on the concept of neurovisceral integration in the overall functioning of an organism, some evidence has emerged suggesting that this integration could be organized asymmetrically, using the autonomic nervous system as a bidirectional communication pathway, whose performance would also be asymmetric. However, the functional significance of this distribution, as well as the evolutionary advantage of an asymmetric nervous organization, is still unknown.

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Functional brain asymmetry, handedness and menarcheal age

Cited by 14 publications

References 13 publications

fMRI reveals alteration of spatial working memory networks across adolescence

fMRI reveals alteration of spatial working memory networks across adolescence

Brain asymmetry, immunity, handedness

Brain Asymmetry: Towards an Asymmetrical Neurovisceral Integration

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