Functional Brain Imaging Based on the Neurovascular Unit for Evaluating Neural Networks after Strok

Abstract

The exploration of human brain function has always been a research hotspot in the field of neuroscience. The concept of a neurovascular unit suggests that cerebral microcirculation can be used as a reliable signal to reflect neural function.Accordingly, functional imaging techniques based on the neurovascular unit are very promising because of their ability to reveal neurovascular coupling and evaluate the functional rehabilitation of cerebrovascular diseases represented by stroke. In the present review, we first describe the role of the neurovascular unit in the injury and repair processes after stroke. We then briefly introduce the relative characteristics and advantages of representative neurovascular unit-based functional imaging. Finally, we summarized the value of these techniques in the evaluation of neural networks after stroke.

Compromised dynamic cerebral autoregulation is a hemodynamic marker for predicting poor prognosis even with good recanalization after endovascular thrombectomy

“…Despite variations in cerebral perfusion pressure and arterial blood pressure, the brain is critically dependent on steady and stable cerebral blood flow because of its finite energy stores. [ 9 10 ] Dynamic cerebral autoregulation (dCA) can protect the brain from ischemic and hyperperfusion damage by adjusting to fluctuating blood pressures. dCA is essential to regulate cerebral hemodynamics, and its dysfunction contributes to the occurrence and progression of stroke[ 11 ] by increasing an individual’s susceptibility to stroke and impairing micro-embolus clearance.…”