Functional disorders of biliary tract in practice of outpatient specialists: optimal treatment choice

Мехтиев, С. Н.; Мехтиева, О. А.

doi:10.33667/2078-5631-2019-4-38(413)-9-18

Cited by 3 publications

(1 citation statement)

References 22 publications

(5 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…В отсутствие этих условий не вполне ясно, можно ли рассматривать замедленное опорожнение ЖП, как отдельную клиническую проблему. Это важные положения, которые нацеливают на дальнейший поиск для понимания рассматриваемой клинической ситуации [5].…”

unclassified

Assessment of the clinical effectiveness of use of hymecromone in combination with ursodeoxycholic acid in biliary pathology

Karimov,

Rustamova,

Sobirova

et al. 2024

ECG

View full text Add to dashboard Cite

The article presents the results of a clinical evaluation of the comparative effectiveness of monotherapy with urosodeoxycholic acid and its combination with himecromone at dosages of 600 mg and 1200 mg in 368 patients with biliary pathology. The study revealed a significant improvement in the indicators of the majority of patients in the observed groups (84.7% in the UDCA group, 85.9% in the UDCA + Gimecromone 600 mg group, 87.9% in the UDCA + Gimecromone 1200 mg group). Evaluation of the effectiveness of gimecromone at a dosage of 600 mg/day and 1200 mg/day in combination with UDCA showed that the relief of symptoms of biliary dysfunction had a dose-dependent effect and the use of gimecromone at a dose of 1200 mg /day had a more pronounced clinical effect.

show abstract

unclassified

Assessment of the clinical effectiveness of use of hymecromone in combination with ursodeoxycholic acid in biliary pathology

Karimov,

Rustamova,

Sobirova

et al. 2024

ECG

View full text Add to dashboard Cite

show abstract

The biliary continuum: an up-to-date look at biliary tract diseases

et al. 2021

View full text Add to dashboard Cite

In the structure of gastrointestinal diseases, the pathology of the hepatobiliary system currently ranks second in frequency of occurrence. The stages of diseases of the biliary system can be combined into the so-called “biliary continuum”, when one patient has a consistent development of pathogenetically related diseases of the biliary tract. The progressive course of functional motility disorders of the biliary tract gradually leads to the development of organic pathology, including chronic cholecystitis, the subsequent development of gallstone disease and possible postcholecystectomy complications. Among the diseases of the biliary system, one of the most frequently used diagnoses is chronic cholecystitis. The development of chronic cholecystitis is associated with repeated attacks of acute inflammation or prolonged irritation of large gallstones. The clinical aspects of chronic cholecystitis and other pathologies included in the the «biliary continuum» largely depends on concomitant dyskinesia. There are several directions for the treatment of pathologies of the biliary system: diet therapy, medication, endoscopic and surgical treatment. According to the latest guidelines, the most important direction in modern therapy of diseases of the biliary system is the restoration of the motility of the biliary tract and the normalization of the physicochemical properties of bile. The central place in the treatment of diseases of the “biliary continuum” is given to antispasmodic drugs. The administration of antispasmodics is recommended in order to relieve biliary pain and dyspeptic symptoms caused by spasm of smooth muscles, as well as to control the inflammatory process due to a decrease in the release of pro-inflammatory substances. This article describes in detail the importance of the recovery of the biliary tract motor activity and the improvement of the physico-chemical properties of bile acids.

show abstract

The role of chronic systemic inflammation in the formation of functional disorders of the biliary tract

Grinevich,,

Kravchuk,

Seliverstov

et al. 2024

Vrach

View full text Add to dashboard Cite

Functional disorders of the biliary tract are included in the group of functional diseases of the digestive system, widespread everywhere, and represent a complex of clinical symptoms developing as a result of motor-tonic dysfunction of the gallbladder, bile ducts and sphincters. Their clinical manifestations are often quite diverse and non-specific. Therefore, the problem of verification, treatment and prevention of this pathology continues to be relevant. In our study, among 37 practically healthy volunteers, in 55% of cases, a functional disorder of the gallbladder of the hypomotor type was detected, correlations of indicators of the motor function of the gallbladder with markers of systemic inflammation were established.

show abstract

Functional disorders of biliary tract in practice of outpatient specialists: optimal treatment choice

Cited by 3 publications

References 22 publications

Assessment of the clinical effectiveness of use of hymecromone in combination with ursodeoxycholic acid in biliary pathology

Assessment of the clinical effectiveness of use of hymecromone in combination with ursodeoxycholic acid in biliary pathology

The biliary continuum: an up-to-date look at biliary tract diseases

The role of chronic systemic inflammation in the formation of functional disorders of the biliary tract

Contact Info

Product

Resources

About