Functional electrical stimulation cycling improves body composition, metabolic and neural factors in persons with spinal cord injury

Griffin, Lisa; Decker, Michael J.; Hwang, Jungyun; Wang, B.; Kitchen, Katie; Ding, Zhenping; Ivy, John L.

doi:10.1016/j.jelekin.2008.03.002

Cited by 206 publications

(189 citation statements)

References 45 publications

(54 reference statements)

Supporting

Mentioning

174

Contrasting

Unclassified

Order By: Relevance

“…FES is one of the most widely studied rehabilitation techniques for the SCI population. The application of FES has shown promise for a variety of SCI-related issues including obesity 62 and muscle atrophy. 63 A total of three papers have investigated acute arterial function changes in response to FES.…”

Section: Resultsmentioning

confidence: 99%

A systematic review of exercise as a therapeutic intervention to improve arterial function in persons living with spinal cord injury

Phillips

Coté

2011

Spinal Cord

View full text Add to dashboard Cite

Study design: All randomized controlled trials, prospective cohort, case-controlled, pre-post studies and case reports that assessed exercise interventions, which influence arterial structure and function after spinal cord injury (SCI), were included. Objective: To review systematically the evidence for exercise as a therapy to alter arterial function in persons with SCI. Setting: Literature searches were conducted for appropriate articles using several electronic databases (e.g. MEDLINE, EMBASE). Methods: Three independent reviewers evaluated each investigation's quality, using the Physiotherapy Evidence Database Scale for randomized controlled trials and Downs and Black Scale for all other studies. Results were tabulated and levels of evidence assigned. Results: A total of 283 studies were found through the systematic literature search. Upon review of the articles, 27 were included. The articles were separated into those investigating arterial benefits, resulting from either acute bouts of exercise or long-term exercise interventions. The ability of both acute and long-term exercise interventions to improve arterial structure and function in those with SCI was supported by limited to moderate methodological quality. Upper body wheeling is the most commonly examined exercise therapy for improving arterial function. It appears from the evidence that a variety of exercise interventions, including passive exercise, upper body wheeling, functional electrical stimulation and electrically stimulated resistance exercise, can improve arterial function in those living with SCI. Conclusions: Although the quality and volume of evidence is low, the literature supports exercise as a useful intervention technique for improving arterial function in those with SCI.

show abstract

Section: Resultsmentioning

confidence: 99%

A systematic review of exercise as a therapeutic intervention to improve arterial function in persons living with spinal cord injury

Phillips

Coté

2011

Spinal Cord

View full text Add to dashboard Cite

show abstract

“…Only 3 subjects were assigned to each group, and no control group was included for comparison. There were 12 studies that reported carbohydrate-related outcomes (9,10,(26)(27)(28)(29)(30)(31)(32)(33)(34)(35) (Table 1) and 15 that reported lipid-related outcomes (9,10,26,27,30,(35)(36)(37)(38)(39)(40)(41)(42)(43)(44) (Table 2). Only 1 study included cardiovascular morbidity as an endpoint (Table 2), and this was assessed using a survey instrument with variable levels of sensitivity and specificity when tested in able-bodied populations (45).…”

Section: Resultsmentioning

confidence: 99%

“…This study also calculated a 15% average reduction in area under the curve (P , 0.05). One FES study identified statistically significant (P 0.05) decreases in blood glucose levels from pretraining to post-training (10 weeks) at 30, 60, and 120 minutes postload (30). Another FES study found differences pre-to post-training (12 weeks) that did not reach statistical significance, but a test for trend was also suggestive of reduced levels (P 5 0.07) (33).…”

Section: Impact Of Exercise Onmentioning

confidence: 99%

“…We identified 16 studies involving 369 individuals that reported lipid- (9,10,26,27,30,(35)(36)(37)(38)(39)(40)(41)(42)(43)(44) or cardiovascular-(45) related outcomes ( Table 2). The overall quality of SCI-specific evidence supporting exercise as a therapy for lipid metabolism disorders was low (46,47).…”

Section: Description Of Exercise Studies With Lipid-or Cardiovascularmentioning

confidence: 99%

“…Six studies examined the effects of active exercise on lipid-related measures (26,27,(36)(37)(38)(39). Only 2 studies examined FES exercise (30,40). Of the intervention studies, only 4 considered baseline lipid levels in analysis or discussion (30,36,38,40).…”

Section: Description Of Exercise Studies With Lipid-or Cardiovascularmentioning

confidence: 99%

See 2 more Smart Citations

Effect of Exercise on Disorders of Carbohydrate and Lipid Metabolism in Adults With Traumatic Spinal Cord Injury: Systematic Review of the Evidence

Carlson

Wilt

Taylor

et al. 2009

The Journal of Spinal Cord Medicine

View full text Add to dashboard Cite

Background/Objective: Carbohydrate and lipid metabolism disorders may affect adults with spinal cord injuries (SCIs) differently than able-bodied individuals because of reduced physical activity in the SCI population. The objective of this study was to conduct a systematic review to determine the effectiveness of exercise to improve carbohydrate and lipid metabolism disorders in adults with chronic SCI. Methods: Studies were identified in MEDLINE (1996MEDLINE ( -2008, Cochrane Library, bibliographies of identified articles, and expert recommendations. English language articles were included if they evaluated adults with chronic SCI; evaluated exercise; and reported carbohydrate-, lipid-, and/or cardiovascular disease-related outcomes. Results: Twenty-two studies met inclusion criteria, including 15 intervention case-series and 7 crosssectional surveys using self-reported physical activity measures. Intervention protocols involved active (n 5 7) or electrically stimulated (n 5 7) exercise or an educational program (n 5 1) from 8 to 52 weeks in duration. Frequency of exercise was typically 2 to 3 sessions/week, lasting 30 to 60 minutes/session. Totals of 150 and 369 subjects participated in studies with carbohydrate (n 5 12) or lipid and cardiovascular (n 5 16) outcomes, respectively; 78% were men. Level of SCI ranged from C4 to L5 and included both incomplete and complete lesions. Outcomes measures included fasting and postload blood glucose and insulin concentrations and serum cholesterol levels. Small sample sizes and variations in study design, intervention, SCI characteristics, and reported outcomes precluded quantitative pooling of results or reliable assessment of metabolic efficacy. No intervention studies assessed cardiovascular outcomes. Conclusions: Evidence is insufficient to determine whether exercise improves carbohydrate and lipid metabolism disorders among adults with SCI. Expert consensus, based on the preliminary evidence, is needed to inform future studies.

show abstract

Endurance neuromuscular electrical stimulation training improves skeletal muscle oxidative capacity in individuals with motor‐complete spinal cord injury

et al. 2017

View full text Add to dashboard Cite

Introduction Spinal cord injury (SCI) results in skeletal muscle atrophy, increases in intramuscular fat, and reductions in skeletal muscle oxidative capacity. Endurance training elicited with neuromuscular electrical stimulation (NMES) may reverse these changes and lead to improvement in muscle metabolic health. Methods Fourteen participants with complete SCI performed 16 weeks of home-based endurance NMES training of knee extensors muscles. Skeletal muscle oxidative capacity, muscle composition, and blood metabolic and lipid profiles were assessed pre- and post-training. Results There was an increase in number of contractions performed throughout the duration of training. The average improvement in skeletal muscle oxidative capacity was 119%, ranging from −14% to 387% (P = 0.019). There were no changes in muscle composition or blood metabolic and lipid profiles. Discussion Endurance training improved skeletal muscle oxidative capacity, however endurance NMES of knee extensor muscles did not change blood metabolic and lipid profiles.

show abstract

Functional electrical stimulation cycling improves body composition, metabolic and neural factors in persons with spinal cord injury

Cited by 206 publications

References 45 publications

A systematic review of exercise as a therapeutic intervention to improve arterial function in persons living with spinal cord injury

A systematic review of exercise as a therapeutic intervention to improve arterial function in persons living with spinal cord injury

Effect of Exercise on Disorders of Carbohydrate and Lipid Metabolism in Adults With Traumatic Spinal Cord Injury: Systematic Review of the Evidence

Endurance neuromuscular electrical stimulation training improves skeletal muscle oxidative capacity in individuals with motor‐complete spinal cord injury

Contact Info

Product

Resources

About