Functional endoscopic sinus surgery improved asthma symptoms as well as PEFR and olfaction in patients with nasal polyposis

Abstract

Functional endoscopic sinus surgery improved nasal and asthma symptoms in patients with nasal polyposis. Functional endoscopic sinus surgery could be considered early in the natural course of nasal polyposis with concomitant asthma, as well as a second-line treatment in nasal polyposis patients with a reduced sense of smell. The potential benefits of FPND 400 microg b.i.d. were probably overshadowed by FESS.

Sinus Surgery and Delivery Method Influence the Effectiveness of Topical Corticosteroids for Chronic Rhinosinusitis: Systematic Review and Meta-Analysis

“…The study authors were contacted via e-mail for raw data in cases of missing data. [17][18][19][20][21][22][23][24][25][26][27][28][29][30] The analyses were based on intention to treat. For missing standard deviations, either 95% CIs, 23,31,32 standard error.…”

“…For missing standard deviations, either 95% CIs, 23,31,32 standard error. 19,21,[33][34][35][36][37] p value, 26 range, 20 or interquartile ranges 18,20 was used for estimation to impute standard deviations. For missing means, medians were converted.…”

“…For missing means, medians were converted. 18,20 The correlation coefficient was calculated in the experimental and control groups from some studies 38,39 and was used to calculate the imputation of standard deviation of change in symptom scores for other studies. 18,[34][35][36] …”

International Consensus Statement on Allergy and Rhinology: Rhinosinusitis

“…319,861,862 Using objective and subjective sinonasal and asthma outcome measures, studies have demonstrated significant clinical improvement following ESS. 320,861,[863][864][865][866] In patients with asthma and NPs, ESS was shown to improve asthma severity scores, reduce the need of inhaled corticosteroids and reduce the frequency of asthma-related emergency room visits. 863 Ehnhage et al 864 showed in a prospective randomized trial that patients with CRSwNP had a significant improvement in nasal and lower airway symptoms after ESS.…”

The use of Postoperative Topical Corticosteroids in Chronic Rhinosinusitis with Nasal Polyps: A Systematic Review and Meta-Analysis

“…24 One cohort study (n ϭ 32) 18 reported normal ACTH levels measured before and 1 hour after removal of corticosteroid-soaked packing gauze. 18 The reported adverse events from the included studies were blood-stained mucus, [22][23][24][25] mild epistaxis, 15,17,19 and nasal dryness. 22,23,26 …”