Functional Evaluation of Larynx Nerve Stimulator With EMG Acquisition Capability and Wireless Connectivity

Telyshev, D. V.; Нестеренко, И. В.; Bochkov, Akim A.; Malinina, Alena; Markov, Aleksandr; Bordovsky, S. P.; Polunin, G V; Ananichuk, Anna; Решетов, И. В.

doi:10.1109/tbcas.2021.3094890

Cited by 1 publication

(1 citation statement)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Neurolaryngology is a young and rapidly evolving subdiscipline in laryngology, which strives towards novel diagnostic and therapeutic options in alignment with general progress in sensor engineering, implantation technology and re-innervation surgery techniques. [1][2][3][4][5] Neuromuscular electrical stimulation (NMES) of the posterior cricoarytenoid muscle (PCA) is a proposed therapeutic concept to treat patients suffering from bilateral vocal fold paresis (BVFP) with synkinesis to restore vocal fold movement. 6 Beginning with proof-of-concept studies in various animal models it has evolved over the past decades to implantable medical devices for first in human trials.…”

Section: Introductionmentioning

confidence: 99%

An Endoscopic Cap Electrode for Posterior Cricoarythenoid Muscle Stimulation in a Porcine Model

et al. 2022

View full text Add to dashboard Cite

ObjectiveLaryngeal pacing (LP) is a highly anticipated therapeutic option for patients suffering from bilateral vocal fold paralysis with synkinesis. Identification of candidate patients requires confirmation of a stimulable posterior cricoidarythenoid muscle (PCA) by neuromuscular electrical stimulation (NMES). A silicone endoscopic cap electrode (ECE50) was designed to be operated as an endoscopic extension tip for selective PCA stimulation and confirmation of a glottic opening movement in a setting comparable to a gastroscopy procedure.MethodsA porcine animal model (n = 6) was applied to develop and test endoscopic cap prototypes in general anesthesia and sedation at a biomedical research center. Two ENT endoscopy experts evaluated and refined the cap design and performance in regard to procedure safety, endoscope handling, accessibility of the PCA by the transoral approach and selective muscle stimulation.ResultsVocal fold opening movements could be evoked by the investigators in 9 of 12 PCA muscles to stimulate with similar electric parameters. The endoscopic approach using the ECE50 proved to be atraumatic and sufficiently controlled under sedation to locate the required hotspot for NMES of the PCA.ConclusionThe functionality of the novel endoscopic cap concept has been proven in a porcine model. It can be expected to be transferable to human application and to be of diagnostic importance in the screening and identification of LP candidate patients in future.Level of EvidenceNA Laryngoscope, 133:2279–2284, 2023

show abstract