2024
DOI: 10.1002/hbm.26678
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Functional gradients reveal cortical hierarchy changes in multiple sclerosis

Alessandro Pasquale De Rosa,
Alessandro d'Ambrosio,
Alvino Bisecco
et al.

Abstract: Functional gradient (FG) analysis represents an increasingly popular methodological perspective for investigating brain hierarchical organization but whether and how network hierarchy changes concomitant with functional connectivity alterations in multiple sclerosis (MS) has remained elusive. Here, we analyzed FG components to uncover possible alterations in cortical hierarchy using resting‐state functional MRI (rs‐fMRI) data acquired in 122 MS patients and 97 healthy control (HC) subjects. Cortical hierarchy … Show more

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