2021
DOI: 10.1371/journal.pone.0255907
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Functional limitations in people with multimorbidity and the association with mental health conditions: Baseline data from the Canadian Longitudinal Study on Aging (CLSA)

Abstract: Introduction Increasing multimorbidity is often associated with declining physical functioning, with some studies showing a disproportionate impact on functioning when mental health conditions are present. More research is needed because most multimorbidity studies exclude mental health conditions. Objectives This study aims to improve our understanding of the association between functional limitation and multimorbidity, including a comparison of those with multimorbidity that includes versus excludes mental… Show more

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Cited by 19 publications
(15 citation statements)
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“…limited, some data suggest that certain clusters, in particular those including mental health conditions (such as depression), are associated with poorer health 80,81 , functional limitations 82 and higher health-care costs compared with other clusters 83 . However, few replication studies have been carried out, and available studies suggest that observed condition clusters are not usually replicable using different methods and/or in different datasets 77,79,[84][85][86] .…”
Section: Complex Multimorbidity 5162mentioning
confidence: 99%
“…limited, some data suggest that certain clusters, in particular those including mental health conditions (such as depression), are associated with poorer health 80,81 , functional limitations 82 and higher health-care costs compared with other clusters 83 . However, few replication studies have been carried out, and available studies suggest that observed condition clusters are not usually replicable using different methods and/or in different datasets 77,79,[84][85][86] .…”
Section: Complex Multimorbidity 5162mentioning
confidence: 99%
“…Several studies demonstrated that functional limitation is common in older adults and increases with age and health conditions, such as cardiopulmonary diseases, neurological conditions, diabetes mellitus, cancer, obesity, dementia, affective disorders and fractures [ 1 , 10 , 23 , 24 ]. In addition, the coexistence of two or more health conditions often creates more disability than would be expected [ 1 , 23 , 25 ].…”
Section: Discussionmentioning
confidence: 99%
“…Several studies demonstrated that functional limitation is common in older adults and increases with age and health conditions, such as cardiopulmonary diseases, neurological conditions, diabetes mellitus, cancer, obesity, dementia, affective disorders and fractures [ 1 , 10 , 23 , 24 ]. In addition, the coexistence of two or more health conditions often creates more disability than would be expected [ 1 , 23 , 25 ]. In this study, the services presented a percentage of combination of comorbidities of 24% in GDH and 19% in GIFRU, and a mixture of clinical diagnoses, such as stroke, Parkinson’s, fractures and neurocognitive disorders.…”
Section: Discussionmentioning
confidence: 99%
“…Multimorbidity can be defined generically as the accumulation of two or more chronic health conditions [ 10 ]. The increasing prevalence of chronic diseases and the rapid ageing of the population has led to an increase in multimorbidity worldwide [ 11 , 12 ], making it one of the greatest challenges for healthcare systems [ 13 , 14 ]. This condition is associated with reduced quality-of-life, increased disability, functional impairment, increased healthcare utilization and fragmentation of care, complex treatment, and increased mortality [ 15 , 16 , 17 ], with the consequent increase in aspects such as health and social costs and poly-medication.…”
Section: Introductionmentioning
confidence: 99%
“…This condition is associated with reduced quality-of-life, increased disability, functional impairment, increased healthcare utilization and fragmentation of care, complex treatment, and increased mortality [ 15 , 16 , 17 ], with the consequent increase in aspects such as health and social costs and poly-medication. Additionally, there are strong associations between having multimorbidity and poorer mental and physical health outcomes [ 18 , 19 ] and a direct association between having multiple physical chronic diseases and consequent common mental disorders [ 12 , 20 , 21 ].…”
Section: Introductionmentioning
confidence: 99%