Functional magnetic resonance imaging to assess neuroadaptation to multifocal intraocular lenses

Rosa, Andreia; Miranda, Ângela; Patrício, Miguel; McAlinden, Colm; Silva, Fátima; Castelo‐Branco, Miguel; Murta, Joaquim

doi:10.1016/j.jcrs.2017.07.031

Cited by 68 publications

(60 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The study published by Kretz et al [21] demonstrated that binocular implantation of diffractive trifocal IOLs (AtLisa tri 839 MP) provides significant VA improvement for all distances and fully functional vision including functional stereopsis, as compared to monocular visual outcome. The 12-month follow-up (longer than in other studies) and longer neuroadaptation time may have contributed to superior CS results in our study [22][23][24][25][26]. Besides neuroadaptation, the other possible explanation for better near CS outcome in AtLisa tri 839 MP group might be major vergence dependence of this IOL as described by Esteve-Taboada [26].…”

Section: Discussionmentioning

confidence: 58%

Comparison of visual outcomes after implantation of AtLisa tri 839 MP and Symfony intraocular lenses

et al. 2020

View full text Add to dashboard Cite

Purpose To compare visual outcomes after implantation of AtLisa tri 839 MP and Symfony intraocular lenses (IOLs). Methods All subjects underwent sequential bilateral cataract extraction with AtLisa tri 839 MP or Symfony IOL implantation. The design is prospective case series. Each group consists of 20 patients (40 eyes). At 1 year postoperatively, the following parameters were analysed: binocular uncorrected visual acuity (log MAR): for distance (UDVA) at 4 m, for intermediate distances (UIVA) at 60, 70, 80 cm and for near (UNVA) at 40 cm, defocus curve, mesopic and photopic contrast sensitivities (CSs), spectacle independence, visual function test questionnaire modified VFQ-25), photopic phenomena and postoperative complications. Results In the AtLisa tri 839 MP group, the mean binocular UNVA and UIVA were significantly better than in the Symfony group (UNVA: − 0.01 ± 0.04 vs. 0.21 ± 0.15; p = 0.000; 60 cm UIVA: − 0.01 ± 0.04 vs. 0.09 ± 0.09, p = 0.001; 70 cm UIVA − 0.05 ± 0.06 vs. 0.11 ± 0.08, p = 0.002; 80 cm UIVA − 0.01 ± 0.06 vs. 0.15 ± 0.08, p = 0.019). There were no significant between-group differences in the mean binocular UDVA and CS, with one exception: the mean binocular distance CS (18 cpd) under mesopic conditions was significantly better in the Symfony group than in the AtLisa tri 839 MP group (1.39 ± 0.22 vs. 1.17 ± 0.27; p = 0.015). The defocus curve analysis revealed significant between-group differences at vergences of 2.0 to − 4.0 D (p < 0.05), except for 2.0, 1.0, 0 and − 1.5. All subjects in AtLisa tri 839 MP group and 18 subjects (90%) in Symfony group were spectacle independent. Patients from both groups highly rated their overall vision quality in the VFQ-25 (1.67 ± 0.47 vs. 1.85 ± 0.5 in the Symfony and AtLisa tri 839 MP group, respectively, p = NS). The scores for daytime driving (1.00 ± 0.00 vs. 1.21 ± 0.36; p = 0.002), night driving (1.57 ± 0.55 vs. 2.13 ± 1.15; p = 0.027) and difficult situation driving (1.14 ± 0.31 vs. 1.53 ± 0.56; p = 0.049) were significantly better in the AtLisa tri 839 MP group than in the Symfony group. The incidence and perception level of halo and glare were significantly reduced (p = 0.00) in the Symfony group as compared to the AtLisa tri 839 MP group. The postoperative course was uneventful in all subjects. Conclusions Visual outcomes achieved with both IOLs are comparable. In both groups, 90% of patients achieved spectacle independence. Whereas the AtLisa tri 839 MP IOL implantation was associated with slightly better intermediate distance VA and significantly better near VA, photic phenomena were less perceived by patients with Symfony IOLs.

show abstract

Section: Discussionmentioning

confidence: 58%

Comparison of visual outcomes after implantation of AtLisa tri 839 MP and Symfony intraocular lenses

et al. 2020

View full text Add to dashboard Cite

show abstract

“…One recent investigation suggested that there is no correlation between the optical properties of an IOL (including total or high-order aberrations) and QoV scores [53]. Patients reporting dysphotic symptoms had increased activity in several regions of the frontoparietal circuits of the brain, including the cingulate gyrus and caudate nucleus [53,54]. Thus, particularly in the field of presbyopia correction, PROs might be of exceptional importantance.…”

Section: Importance Of Prosmentioning

confidence: 99%

Methods for evaluating quality of life and vision in patients undergoing lens refractive surgery

Grzybowski

Kanclerz²,

Muzyka−Woźniak³

2019

Graefes Arch Clin Exp Ophthalmol

View full text Add to dashboard Cite

Purpose Cataract surgery has evolved into a procedure that generally yields the best postoperative refractive result attainable. Patients with multifocal intraocular lenses (IOLs) present higher rates of spectacle independence, although reduced intermediate vision, dysphotopsias, and a loss of image quality might also be experienced. The aim of the study was to review the methods for assessing quality of life and vision in patients undergoing lens refractive surgery in randomized controlled trials. Methods We reviewed the PubMed web platform to identify relevant studies using the following keywords: quality of life, quality of vision, lens surgery, lens exchange, refractive lens exchange, cataract, cataract surgery, intraocular lens, IOL, multifocal, and monovision. Results An increasing number of studies have focused on patient-reported outcomes (PROs). Only a few of the available visual function questionnaires can be regarded as useful in lens refractive surgery with multifocal IOL implantation. Many selfdeveloped questionnaires have emerged that have not been adequately validated or found to feature properly evaluated repeatability, hampering the possibility of comparing outcomes. Conclusions This review describes the existing PROs instruments and informs the choice of an appropriate measure in lens refractive surgery. Rasch-developed tools should be utilized for measuring quality of life and vision in patients undergoing lens refractive surgery and there is a number of highly robust tools available.

show abstract

“…It is unclear whether any of these myopia control methods may have caused long-term or sustained changes in visual function, although the visual system has been shown to adapt to changes in the optics of the eye over time. 37 – 40 …”

Section: Introductionmentioning

confidence: 99%

“…Additionally some form of neuroadaptation may occur during DIMS wear, which compensates for optical deficiencies in the retinal image. 37 – 40 Although advantageous during DIMS wear, this adaptation might degrade visual performance. The current study therefore aimed to compare the 2-year changes in visual function in myopic children who normally wore either DIMS lenses or regular SV spectacle lenses to determine whether wearing DIMS lenses results in a change in visual function.…”

Section: Introductionmentioning

confidence: 99%

Effect of Defocus Incorporated Multiple Segments Spectacle Lens Wear on Visual Function in Myopic Chinese Children

Lam

Tang

Hua

et al. 2020

Trans. Vis. Sci. Tech.

View full text Add to dashboard Cite

Purpose To compare visual function of myopic children who had worn either defocus incorporated multiple segment (DIMS) spectacle lenses or single vision (SV) spectacle lenses over two years. Methods We included 160 Chinese myopic (−1 diopter [D] to −5 D) children aged 8 to 13 years in a randomized clinical trial; they wore either DIMS lenses (DIMS; n = 79) or regular SV spectacles lenses ( n = 81) full time for 2 years. Visual function, including high-contrast visual acuity (VA) and low-contrast VA at distance and near, binocular functions, and accommodation, before, during, and after 2 years of spectacle wear were assessed when both groups wore SV corrections. Changes of visual function between the two groups and within groups were compared. Results There were no statistically significant differences in the 2-year visual function changes between DIMS and SV groups (repeated measures analysis of variance with group as factor; P > 0.05). Statistically significant improvement in the best-corrected distance high-contrast VA ( P < 0.001) and stereoacuity score ( P < 0.001) were found after DIMS lens wear over 2 years. Similar findings were observed after SV spectacle lens wear. For both the DIMS and SV groups, there were statistically significant decreases in accommodative lag, monocular and binocular amplitude of accommodation after two years ( P < 0.01), but not in the changes in distance low-contrast VA, near high-contrast VA, near low-contrast VA, or phoria. Conclusions Although changes in some visual function were shown during 2 years of DIMS lens wear, similar changes were found with SV lens wear. Wear of DIMS spectacle lenses for 2 years does not adversely affect major visual function when children return to SV corrections. Translational Relevance DIMS spectacle lenses did not cause any adverse effects on visual function.

show abstract

Functional magnetic resonance imaging to assess neuroadaptation to multifocal intraocular lenses

Cited by 68 publications

References 14 publications

Comparison of visual outcomes after implantation of AtLisa tri 839 MP and Symfony intraocular lenses

Comparison of visual outcomes after implantation of AtLisa tri 839 MP and Symfony intraocular lenses

Methods for evaluating quality of life and vision in patients undergoing lens refractive surgery

Effect of Defocus Incorporated Multiple Segments Spectacle Lens Wear on Visual Function in Myopic Chinese Children

Contact Info

Product

Resources

About