Functional properties of bioactive compounds from Spirulina spp.: Current status and future trends

Bortolini, Débora Gonçalves; Maciel, Giselle Maria; Fernandes, Isabela de Andrade Arruda; Pedro, Alessandra Cristina; Rúbio, Fernanda; Brancod, Ivanise Guiherme; Haminiuk, Charles Windson Isidoro

doi:10.1016/j.fochms.2022.100134

Cited by 52 publications

(28 citation statements)

References 69 publications

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“…Type I and II collagen derived from microalgae Spirulina sp. (Darvin et al, 2015;Bortolini et al, 2022) has also shown promise as a biomaterial for scaffolds and hydrogels to repair bone damage (Li et al, 2021). Further clinical studies and using more advanced technological methods with algal biomaterials in the bone tissue engineering field are strongly encouraged.…”

Section: Green Algaementioning

confidence: 99%

Algal-derived macromolecules and their composites: From synthetic biology to biomedical applications in bone and cardiovascular tissue engineering

Mayulu

Taslim²,

Hardinsyah³

et al. 2023

F1000Res

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Algae have shown numerous advantages as biofunctional and bioactive material sources. The development of biosynthetic or synthetic materials has enabled algal-derived macromolecules and their derivatives to be used in biomedical applications. This review examines and analyzes the most recent developments in the production of biomaterials from algal-derived macromolecules and their composites and their potential applications in bone and cardiovascular tissue engineering. Several macromolecules derived from algal polysaccharides, including sulfated polysaccharides, fucoidans, and fucans, have been developed for cartilage, intervertebral disc, bone, and skeletal muscle transplants because of their stable structures. Alginates, fucoidans, chitin, porphyrin, and other algal polysaccharide derivatives have been investigated for engineering blood vessels, heart valves, and even the liver. One advantage of algal-derived macromolecules and composites is their safe immunity properties. This review also highlights cutting-edge developments in applying algal-derived macromolecules with a broader biomedical scope to encourage in-depth research into their potential as biomaterial scaffolds in medical applications.

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Section: Green Algaementioning

confidence: 99%

Algal-derived macromolecules and their composites: From synthetic biology to biomedical applications in bone and cardiovascular tissue engineering

Mayulu

Taslim²,

Hardinsyah³

et al. 2023

F1000Res

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Section: Anti-cancer Propertiesmentioning

confidence: 99%

“…In addition to its other health benefits, microalgae have been shown to improve the immune system and have anticancer properties (9). Several studies have been conducted that demonstrate its cancer-fighting properties in both animal and human studies (9,(53)(54)(55). In vitro studies are suggestive of the fact that the unique polysaccharide of Spirulina enhances cell nucleus enzyme activity and DNA repair synthesis (49).…”

Section: Anti-cancer Propertiesmentioning

confidence: 99%

“…It is normally known to grow naturally in high salt alkaline water, mostly in tropical and subtropical areas of America, Mexico, Africa and Asia (8). Among its vast varieties, the most commonly studied are; Spirulina platensis (Arthrospora platensis), Spirulina maxima (Arthrospora maxima) and Spirulina fusiformis (Arthrospora fusiformis) (9).…”

Section: Introductionmentioning

confidence: 99%

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Spirulina, an FDA-approved functional food: Worth the hype?

Ahmad¹,

Intikhab²,

Zafar³

et al. 2023

Cell Mol Biol (Noisy-le-grand)

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“…It has been extensively studied since 1960, cyanobacteria being a well-known source of proteins, essential amino acids, vitamins, β-carotene, minerals, polysaccharides, essential fatty acids, sulfolipids and phycocyanin (Shabana et al, 2017;Bortolini et al, 2022).…”

Section: Introductionmentioning

confidence: 99%

Spirulina (Arthrospira) Platensis - A Review of Possible Hypotriglyceridemic Effects

ANTON¹,

IVAN²,

LOGHIN³

et al. 2023

AMBS

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Spirulina (Arthrospira) sp. is a blue-green algae that is often used as a dietary supplement in powder or tablet form because of its beneficial nutrients, lack of toxicity and therapeutic effects. This study investigates its effects on subjects supplemented with Spirulina, focusing on its effects on triglyceride values. A literature review was conducted on the effects of Spirulina on different organisms, with a focus on triglycerides. Most research with Spirulina sp. has shown that it has a hypotriglyceridemic effect on patients given Spirulina, but also on some animals, with numerous studies also done on rats. Following analysis, it has been found that Spirulina supplementation has a favorable effect on triglycerides, lowering their value considerably, leading to a reduced risk of cardiovascular disease and stroke. The microalga Spirulina sp. has been the subject of research due to evidence of its therapeutic potential in several areas, including its ability to prevent and reduce damage caused by dyslipidemia and its antioxidant activity. The present study suggests that Spirulina supplementation may produce beneficial effects on triglycerides.

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Functional properties of bioactive compounds from Spirulina spp.: Current status and future trends

Cited by 52 publications

References 69 publications

Algal-derived macromolecules and their composites: From synthetic biology to biomedical applications in bone and cardiovascular tissue engineering

Algal-derived macromolecules and their composites: From synthetic biology to biomedical applications in bone and cardiovascular tissue engineering

Spirulina, an FDA-approved functional food: Worth the hype?

Spirulina (Arthrospira) Platensis - A Review of Possible Hypotriglyceridemic Effects

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