Functional properties of chitosan films modified by snail mucus extract

Filippo, Maria Francesca Di; Panzavolta, Silvia; Albertini, Beatrice; Bonvicini, Francesca; Gentilomi, Giovanna Angela; Orlacchio, Ramona; Passerini, Nadia; Bigi, Adriana; Dolci, Luisa Stella

doi:10.1016/j.ijbiomac.2019.11.230

Cited by 42 publications

(35 citation statements)

References 41 publications

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“…Apart from biocompatibility and biodegradability, polysaccharides are susceptible to chemical modification, which allows their structure and properties to be tailored into the form required for their further use [ 3 , 4 ]. This approach can be seen in many fields of science and, in particular, in the design and synthesis of materials for medicine, pharmacy, and biological applications [ 5 , 6 , 7 ].…”

Section: Introductionmentioning

confidence: 99%

Crosslinking of Chitosan with Dialdehyde Chitosan as a New Approach for Biomedical Applications

Węgrzynowska-Drzymalska

Grebicka

Mlynarczyk

et al. 2020

Materials

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Materials based on natural high molecular compounds are particularly interesting for biomedical applications. It is known that the cross-linking agent used for preparation of biomacromolecule-based materials is as important as used biopolymer. Therefore, natural cross-linkers containing reactive carbonyl groups are of great interest especially for modifying properties of natural polysaccharides. One of the most popular cross-linking agents is glutaraldehyde. Nevertheless, the unreacted particles can be released from the cross-linked material and cause cytotoxic effects. This can be eliminated when using a cross-linker based e.g., on polysaccharides. This article describes quick and efficient synthesis of dialdehyde chitosan (DACS) and its application for the preparation of chitosan films. Materials obtained with different amount of DACS were fully characterized in terms of structure and surface morphology. Thermal and mechanical properties as well as hydrophilic character were also examined. The results obtained were compared with the materials obtained by cross-linking chitosan with low molecular weight glutaraldehyde and high molecular weight cross-linking agent based on polysaccharide–dialdehyde starch. Toxicity of all obtained materials was tested using the Microtox® test. It has been shown that due to better mechanical, thermal and surface properties as well as lower toxicity, dialdehyde chitosan is a very promising crosslinking agent.

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Section: Introductionmentioning

confidence: 99%

Crosslinking of Chitosan with Dialdehyde Chitosan as a New Approach for Biomedical Applications

Węgrzynowska-Drzymalska

Grebicka

Mlynarczyk

et al. 2020

Materials

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“…Finally, XRD (X-ray diffraction) and SEM (Scanning Electron Microscopy) analyses were carried out in order to assess the film structure. The three characteristic peaks of chitosan were observed at 9°, 12°, and 20° [ 8 ] for all the chitosan films under study, regardless of the addition of EPS ( Figure 3 ).…”

Section: Resultsmentioning

confidence: 99%

“…In particular, the addition of essential oils from two aromatic herbs into chitosan films enhanced their antioxidant and antibacterial activity [7]. Snail mucus extract, a substance that is widely used in cosmetics formulations for its protective and reparative activities, has also been incorporated into chitosan-based films to modulate their properties [8]. Recently, chitosan films have shown their biocompatibility and wound healing capacity [9], suggesting their potential to develop more sophisticated wound dressings based on chitosan, including other bioactive molecules.…”

Section: Introductionmentioning

confidence: 99%

Chitosan Films Incorporated with Exopolysaccharides from Deep Seawater Alteromonas sp.

Zarandona

Estupiñán²,

Perez³

et al. 2020

Marine Drugs

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Two Alteromonas sp. strains isolated from deep seawater were grown to promote the production of exopolysaccharides (EPS, E611 and E805), which were incorporated into chitosan solutions to develop films. The combination of the major marine polysaccharides (chitosan and the isolated bacterial EPS) resulted in the formation of homogenous, transparent, colorless films, suggesting good compatibility between the two components of the film-forming formulation. With regards to optical properties, the films showed low values of gloss, in the range of 5–10 GU, indicating the formation of non-glossy and rough surfaces. In addition to the film surface, both showed hydrophobic character, with water contact angles higher than 100 º, regardless of EPS addition. Among the two EPS under analysis, chitosan films with E805 showed better mechanical performance, leading to resistant, flexible, easy to handle films.

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“…With the continuous development of chemistry and other disciplines, many new technologies and ideas have been developed 81,82 . For example, in natural medicinal chemistry, it has been found that active ingredients exist in many plants; in material chemistry, many nanoparticles with unique activities have been successfully synthesized; in chemical synthesis, food additives have been synthesized and successfully used in practice.…”

Section: Applications Of Chitosan Films In Food Industrymentioning

confidence: 99%

Chitosan‐based biomaterials: From discovery to food application

Tian

Liu

2020

Polymers for Advanced Techs

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Due to higher expectations for health in recent decades, the issues of food preservation and safety are now attracting more and more attention. Therefore, research and development of food packaging materials is of important practical significance. While the wide use of functional plastic packaging brings great convenience to the food industry, serious problems also appear subsequently, such as source exhaustion, plasticizer transfer, and other potential food safety hazards, which pose great challenges to researchers. In order to overcome these shortcomings, the natural polysaccharide chitosan has emerged as a suitable food packaging material. Chitosan has many excellent properties such as biodegradability, biocompatibility, bioactivity, nontoxicity, and polycationic nature. This article reviews the discovery and preparation process of chitin and chitosan. In addition, the application of chitosan‐based films in food storage is highlighted. Finally, the future perspectives of chitosan are proposed.

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Functional properties of chitosan films modified by snail mucus extract

Cited by 42 publications

References 41 publications

Crosslinking of Chitosan with Dialdehyde Chitosan as a New Approach for Biomedical Applications

Crosslinking of Chitosan with Dialdehyde Chitosan as a New Approach for Biomedical Applications

Chitosan Films Incorporated with Exopolysaccharides from Deep Seawater Alteromonas sp.

Chitosan‐based biomaterials: From discovery to food application

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