“…Out of the total TTTS cohort examined, the prevalence of PA (3.9%) and PS (2.6%) is much higher than reported in the general population (1/12 000 and 1/5300 live births for PA and PS, respectively). 23 In addition, the prevalence of isolated PI (2.1%) is four times that seen in the normal fetus (0.54%) as reported by Smrcek et al 24 The etiology of RVOT abnormalities in TTTS, however, remains speculative. Most patients with RVOT anomalies are Quintero stage III and IV, which suggests that RVOT abnormality is associated with more severe TTTS.…”