2024
DOI: 10.1101/2024.03.21.586120
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Functional Redundancy inCandida aurisCell Surface Adhesins Crucial for Cell-Cell Interaction and Aggregation

Tristan W. Wang,
Dimitrios Sofras,
Daniel Montelongo-Jauregui
et al.

Abstract: Candida auris is an emerging nosocomial fungal pathogen associated with life-threatening invasive disease due to its persistent colonization, high level of transmissibility and multi-drug resistance. Aggregative and non-aggregative growth phenotypes for C. auris strains with different biofilm forming abilities, drug susceptibilities and virulence characteristics have been described. Using comprehensive transcriptional analysis we identified key cell surface adhesins that were highly upregulated in the aggregat… Show more

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