Functional results after endothelial queratoplasty: three years of experience

Villarrubia, Alberto; Palacín, Elisa; Aránguez, C.; Solana, J.; García‐Alonso, Carlos R.

doi:10.1016/s2173-5794(11)70009-3

Cited by 2 publications

(4 citation statements)

References 21 publications

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“…But according to Villarrubia et al (2011), graft thickness does not influence BSCVA. Furthermore, increased corneal aberrations of the posterior surface have to be considered, which could be related to visual acuity following DSAEK or the formerly performed deep lamellar endothelial keratoplasty (DLEK) (Hindman et al 2007;Muftuoglu et al 2010;Yamaguchi et al 2011).…”

Section: Discussionmentioning

confidence: 91%

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Correlation between visual acuity and interface reflectivity measured by pentacam following DSAEK

Heinzelmann¹,

Böhringer²,

Maier³

et al. 2013

Acta Ophthalmologica

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. Purpose: Descemet‐stripping automated endothelial keratoplasty (DSAEK) is an advanced method of lamellar endothelial keratoplasty. In comparison with penetrating keratoplasty, visual rehabilitation seems to be faster. Final visual outcome of DSAEK, however, seems to be limited, especially in comparison with Descemet membrane endothelial keratoplasty (DMEK). DSAEK cases without graft failure often do not show any definite correlate for the reduced optical performance. In this study, we tried to correlate visual acuity following DSAEK with interface reflectivity as measured by a rotating Scheimpflug system. Methods: We examined 14 eyes of 13 patients with the pentacam for 2–11 months following DSAEK. Reflectivity of the interface region in the centre of the optical axis as well as central corneal thickness was determined. Statistical correlation between interface reflectivity and best spectacle‐corrected visual acuity, central corneal thickness and follow‐up time was drawn (multifactorial linear regression analysis). Results: Statistically significant correlation between interface reflectivity and BSCVA as well as follow‐up time was found. Reflectivity was highest in regions of interface (metal) particles. There was no statistically significant correlation between interface reflectivity and central corneal thickness. Conclusion: We present a measurable correlate for reduced visual outcome following DSAEK despite a clear graft. Inverse correlation between interface reflectivity and best spectacle‐corrected visual acuity (BSCVA) indicates that irregularities or scarring in the interface region may influence the optical quality following DSAEK.

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Section: Discussionmentioning

confidence: 91%

“…One possible explanation may be increased total corneal thickness because of thick grafts following DSAEK. But according to Villarrubia et al. (2011), graft thickness does not influence BSCVA.…”

Section: Discussionmentioning

confidence: 91%

Correlation between visual acuity and interface reflectivity measured by pentacam following DSAEK

Heinzelmann¹,

Böhringer²,

Maier³

et al. 2013

Acta Ophthalmologica

View full text Add to dashboard Cite

show abstract

“…The influence of endothelial graft thickness on visual acuity in DSAEK is controversial, with some authors reporting better results with thinner grafts and others finding no correlation (10)(11)(12)(13)(14)(15). However, studies evaluating this subject have either focused on relatively thick grafts (160-170 µm) or on grafts prepared by manual dissection (11)(12)(13)(14)(15). When grafts having less than 130 µm are evaluated, a positive correlation between thickness and visual acuity is obtained (9,10), suggesting that an effect may exist under a certain thickness.…”

Section: Methodsmentioning

confidence: 99%

“…This may be caused by interface irregularity, the presence of donor posterior stroma, or a thick endothelial graft (7–9). The influence of endothelial graft thickness on visual acuity in DSAEK is controversial, with some authors reporting better results with thinner grafts and others finding no correlation (10–15). However, studies evaluating this subject have either focused on relatively thick grafts (160–170 μm) or on grafts prepared by manual dissection (11–15).…”

Section: Introductionmentioning

confidence: 99%