Abstract:It has been known that androgens and estrogens, which are referred to as sex steroids, make many effects on two major nasal chemosensory mucosae such as olfactory mucosa and vomeronasal organ. Our studies conducted in rodents have demonstrated that two of the constituent cells in the olfactory mucosa, sustentacular cells and acinar cells in the associated glands of the olfactory mucosa, Bowman’s glands, express four different enzymes involved in the biosynthesis of estradiol-17β (E2). Furthermore, our ongoing … Show more
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