“…These studies measured global function with the Sickness Impact Profile 68 (SIP68) in persons with limb loss from the Netherlands. 2,3,60 Studies of persons with limb loss have reported impaired global function using the SIP136 in persons with limb loss from the Lower Extremity Assessment Project (LEAP), 4,5,10 persons with diabetes and vascular limb loss from Texas, 6 and persons with limb loss from the Netherlands. 7,9 Participants in the LEAP study were male 81.5%, White 73.0%, Black 19.7%, and other race/ethnicity 7.3%, with over half under age 35 years who had undergone traumatic amputations at one of eight level one trauma centers throughout the United States.…”