Functional swallowing outcomes following treatment for oropharyngeal carcinoma: a systematic review of the evidence comparing trans‐oral surgery versus non‐surgical management

Abstract

From the current evidence, no direct comparisons could be made of swallowing outcomes between the surgical and non-surgical modalities. Swallowing is a multidimensional construct, and the range of assessments utilised by authors reflects the variety of available reporting methods. The MD Anderson Dysphagia Inventory is a subjective measure that allows limited comparison between the currently available heterogeneous data, and is explored in detail. The findings highlight that further research may identify the most appropriate tools for measuring swallowing in patients with OPSCC. Consensus should allow their standardised integration into future studies and randomised control trials.

Up-front and Salvage Transoral Robotic Surgery for Head and Neck Cancer: A Belgian Multicenter Retrospective Case Series

“…On the other hand, mean follow-up of TORS studies is short when compared to conservative organ preservation studies, possibly favoring the definitive functional outcome after TORS. Moreover, direct comparisons of swallowing outcomes between patients treated with any kind of transoral surgery, including TORS, and non-surgical treatment is not possible because of the varying methodology and heterogeneity of swallowing outcome measures used ( 29 ). In this respect, the presumed functional superiority of TORS versus non-surgical treatments remains to be critically appraised until level I evidence will be available.…”

Helical intensity‐modulated radiotherapy with concurrent chemotherapy for oropharyngeal squamous cell carcinoma: A prospective investigation of acute swallowing and toxicity patterns

“…2 Currently, chemoradiotherapy (CRT) is considered the standard of care for locally advanced oropharyngeal SCC, 3,4 offering 5-year survival rates of 74% for HPV-positive disease 5 with the benefit of organ function preservation. 6,7,10,[13][14][15] Oropharyngeal dysphagia is of particular concern for this patient group, 16,17 with aspiration pneumonia an underreported consequence of CRT for oropharyngeal SCC. 6,7 Within this population, pain, mucositis, dysphagia, dysgeusia, xerostomia, thick saliva, nausea, fatigue, and dermatitis are frequently reported during treatment, whereas xerostomia, dysphagia, fibrosis, and pain can become chronic issues known to negatively influence quality of life (QOL).…”

“…6,[8][9][10][11][12] Grade 3 mucositis during CRT for oropharyngeal SCC is common, with incidence rates ranging from 21%-80% reported in the literature. 6,7,10,[13][14][15] Oropharyngeal dysphagia is of particular concern for this patient group, 16,17 with aspiration pneumonia an underreported consequence of CRT for oropharyngeal SCC. 18,19 Oropharyngeal tumors are associated with greater difficulty in managing semisolid diets, 20 with one-third to two-thirds of patients experiencing grade 3 dysphagia requiring enteral nutrition support when undergoing CRT using intensity-modulated radiotherapy (IMRT).…”

Cáncer de laringe: Serie de casos en 6 años en el Complejo Asistencial Doctor Sótero del Río

“…Los principales factores de riesgo asociados son el tabaco y el alcohol 6 . Asimismo, se ha visto una alza en la incidencia del cáncer escamoso de vía aerodigestiva superior que se ha atribuido a la infección por virus papiloma humano [6][7] .…”