Functional treatment of temporal bone chondroblastoma: retrospective analysis of 3 cases

Vinciguerra, Alessandro; Vérillaud, Benjamin; Eliezer, Michaël; Kaci, Rachid; Kania, Romain; Herman, Philippe

doi:10.1007/s00405-020-06203-4

Cited by 6 publications

(4 citation statements)

References 10 publications

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“…Over the past years, typical clinical manifestations have been described such as vertigo, diplopia, facial paresthesia/paresis, otitis media, tinnitus, hearing loss, and headache [ 6 , 7 ]. Even if the latter two are generally described as being the most frequent, correct interpretation of headache should be carefully considered since multiple causes of cephalic pain are possible, and its specific link with the pathologic process should be carefully considered [ 2 , 8 ]. It has been pointed out that headache is common, and efforts should be made to determine if it is directly related to PACG [ 2 , 4 ].…”

Section: Discussionmentioning

confidence: 99%

Typical and Atypical Symptoms of Petrous Apex Cholesterol Granuloma: Association with Radiological Findings

Vinciguerra

Turri‐Zanoni

Vérillaud

et al. 2022

JCM

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Objective: Petrous apex cholesterol granuloma (PACG) is a lesion that can give rise to different symptoms, and correlations with etiopathology are ambiguous. The aim of this study is to analyze the association between PACG symptoms and radiological findings at presentation, in order to establish a reproduceable pre-operative radiological evaluation and guide the surgical indication. Methods: PACG patients were collected in two tertiary care hospitals. All cases underwent CT/MRI to evaluate the cyst localization and erosion of surrounding structures. Typical and atypical symptoms were then analyzed and compared to radiologic findings established in accordance with the literature. Results: Twenty-nine patients were recruited; the most common symptoms were headache (69%), diplopia (20.7%) and fainting (24.1%), an atypical clinical manifestation related to jugular tubercle involvement. Significant associations between symptoms and radiologic findings were noted in terms of headache and temporal lobe compression (p = 0.04), fainting and jugular tubercle erosion (p < 0.001), vestibular symptoms and internal auditory canal erosion (p = 0.02), facial paresthesia and Meckel’s cave compression (p = 0.03), diplopia and Dorello canal involvement (p = 0.001), and tinnitus and cochlear basal turn erosion (p < 0.001). All patients were treated via an endoscopic–endonasal approach, in which extension was tailored to each case. At a median follow-up of 46 months, 93.1% of patients experienced resolution of symptoms. Conclusions: This clinico-radiological series demonstrates associations between symptoms and anatomical subsites involved with PACG. Hence, it may guide the surgeon at the time of surgical decision, since it asserts that typical and atypical symptoms are actually related to PACG.

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Section: Discussionmentioning

confidence: 99%

Typical and Atypical Symptoms of Petrous Apex Cholesterol Granuloma: Association with Radiological Findings

Vinciguerra

Turri‐Zanoni

Vérillaud

et al. 2022

JCM

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“…Hearing loss (especially the conductive type), tinnitus, cranial nerve involvement, facial swelling, and otalgia are the most common symptoms ( 4 , 6 , 7 ). TMJ dysfunction can also be seen.…”

Section: Discussionmentioning

confidence: 99%

“…One case had recurrence after 125 months of follow-up and was treated with RT successfully (gamma knife radiosurgery; maximum dose of 23 Gy). No recurrence occurred in the following 100-month period (total follow-up period was 225 months) ( 7 ). However, in our case, total removal was not possible and control MRI showed residual tumor growth thus warranting RT as the best alternative treatment modality with many reports showing its effectiveness in tumor growth control ( 9 ).…”

Section: Discussionmentioning

confidence: 99%

Promising Outcome of Radiation Therapy for Chondroblastoma of Temporal Bone in Childhood: A Case Report

Öçal¹,

Satar²,

Çelik³

et al. 2022

TAO

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Chondroblastoma is a rare cartilaginous benign bone tumor. Chondroblastoma in the temporal bone is also quite rare. Total excision is the main treatment. Data regarding tumor response to radiation therapy (RT) is insufficient. We describe a case of chondroblastoma that was treated with RT following subtotal tumor resection. In this case, the patient was a 14-year-old male who presented with a three-month history of ear fullness and hearing loss in his right ear. Magnetic resonance imaging revealed a mass partly filling the right external auditory canal and the inferior part of the middle ear. Histopathological findings indicated chondroblastoma. Subtotal tumor resection was performed due to risk of complications. RT was planned upon the growth of the tumor during follow-up. Treatment with subtotal resection and postoperative RT has been successful and the patient had no recurrence in the course of the 12-year follow-up. In chondroblastoma, complete surgical resection is still the gold standard. But the success of subtotal resection followed by adjuvant RT should also be kept in mind for cases where the total excision would pose high morbidity.

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“…Managing metastatic chondroblastoma poses unique challenges due to its rarity and the potential involvement of multiple organ systems. Treatment strategies aim to control tumor growth, alleviate symptoms, preserve function, and improve the overall quality of life [ 80 ]. While no standard guidelines exist for metastatic chondroblastoma, therapeutic decisions are typically individualized based on factors such as tumor burden, extent of metastasis, the patient’s overall health, and treatment goals.…”

Section: Treatment Approaches For Metastatic Chondroblastomamentioning

confidence: 99%

Comprehensive Insights into Chondroblastoma Metastasis: Metastatic Patterns and Therapeutic Approaches

Samargandi,

Bafail,

Le Nail

et al. 2024

Cancers

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Chondroblastoma metastasis, though rare, represents a clinically significant and notably important aspect of bone tumors. Understanding its epidemiological characteristics, pathological features, and treatment modalities, despite its infrequency, is imperative for comprehensive patient management. This review aims to elucidate the epidemiology, molecular mechanisms, diagnostic challenges, and therapeutic strategies associated with chondroblastoma metastasis. The patterns, prognostic factors, and treatment outcomes were explored through an analysis of case studies and clinical reports. Notably, we highlighted emerging therapeutic perspectives aimed at improving patient outcomes. To the best of our knowledge, there has been no previous review addressing these matters cumulatively, highlighting a significant gap in the existing scholarly literature. By shedding light on the nuances of chondroblastoma metastasis, this review contributes to the advancement of knowledge in this field and informs clinical decision-making for improved patient care.

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Functional treatment of temporal bone chondroblastoma: retrospective analysis of 3 cases

Abstract: Purpose To describe and analyse functional treatment of temporal bone chondroblastoma (TBCh).

Cited by 6 publications

References 10 publications

Typical and Atypical Symptoms of Petrous Apex Cholesterol Granuloma: Association with Radiological Findings

Typical and Atypical Symptoms of Petrous Apex Cholesterol Granuloma: Association with Radiological Findings

Promising Outcome of Radiation Therapy for Chondroblastoma of Temporal Bone in Childhood: A Case Report

Comprehensive Insights into Chondroblastoma Metastasis: Metastatic Patterns and Therapeutic Approaches

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