2020
DOI: 10.3389/fnins.2019.01384
|View full text |Cite
|
Sign up to set email alerts
|

Functional Ultrasound (fUS) During Awake Brain Surgery: The Clinical Potential of Intra-Operative Functional and Vascular Brain Mapping

Abstract: Background and Purpose: Oncological neurosurgery relies heavily on making continuous, intra-operative tumor-brain delineations based on image-guidance. Limitations of currently available imaging techniques call for the development of realtime image-guided resection tools, which allow for reliable functional and anatomical information in an intra-operative setting. Functional ultrasound (fUS), is a new mobile neuro-imaging tool with unprecedented spatiotemporal resolution, which allows for the detection of smal… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
4
1

Citation Types

0
57
0
1

Year Published

2020
2020
2024
2024

Publication Types

Select...
5
1
1

Relationship

1
6

Authors

Journals

citations
Cited by 82 publications
(58 citation statements)
references
References 42 publications
0
57
0
1
Order By: Relevance
“…In creating sparse sequences, we chose to select only the initial portion of the original sequence over zeroing interleaved frames (e.g., discarding 3 frames every 4 in the case of 25% density) to take advantage of the shorter observation window. This approach has the benefit of reducing the occurrence of motion artifacts and signal degradation due to data scrubbing, which are inevitable factors in mobile rodent fUS imaging experiments 7,44 and handheld applications 5 and are more likely to appear with longer observation times.…”
Section: Discussionmentioning
confidence: 99%
See 3 more Smart Citations
“…In creating sparse sequences, we chose to select only the initial portion of the original sequence over zeroing interleaved frames (e.g., discarding 3 frames every 4 in the case of 25% density) to take advantage of the shorter observation window. This approach has the benefit of reducing the occurrence of motion artifacts and signal degradation due to data scrubbing, which are inevitable factors in mobile rodent fUS imaging experiments 7,44 and handheld applications 5 and are more likely to appear with longer observation times.…”
Section: Discussionmentioning
confidence: 99%
“…Similar to blood oxygen level dependent functional magnetic resonance imaging (BOLD fMRI), the detected fUS hemodynamic response provides an indirect measurement of local spiking activity via neurovascular coupling 2 . However, fUS has higher sensitivity and spatiotemporal resolution than fMRI and uses more affordable and portable equipment, opening the possibility for functional neuroimaging performed directly at the bedside [3][4][5] .…”
Section: Introductionmentioning
confidence: 99%
See 2 more Smart Citations
“…Such flow imaging techniques have yielded valuable information in selected applications, for instance in diagnoses of retinal disorders using OCT angiography (OCTA) [3] , [4] , [5] and of cardiac valve insufficiency using Color Doppler echocardiography [6] , [7] . Recent years have seen an intensive research effort directed at microvascular brain imaging using Power Doppler ultrasound, which allows non- or mildly invasive assessment of functional neurological response from rodents to humans [8] , [9] , [10] , [11] .…”
Section: Introductionmentioning
confidence: 99%