Shelf-stable snacks are available almost everywhere and are generally carbohydrate and refined sugar-based and lack good quality proteins (Amrein et al., 2021;Raja et al., 2014). Consumption of unhealthy energy-dense snacks is an important risk factor for obesity and related chronic diseases, such as diabetes, stroke, or cancer (WHO, 2018). Snacking has been reported to contribute up to a third of daily energy intake and there is a need for the development of healthy snacks having good quality proteins, a good fat profile, and immune-boosting capacity that has become particularly important in wake of the recent pandemic of SARS-CoV-2 (Aggarwal, 2020;Reynolds, 2018; Skoczek-Rubińska et al., 2021). Maintaining higher immunity and health status through increased and regular consumption of functional foods rich in nutraceuticals and immune boosters is now a general consensus among medical experts and nutritionists in different countries (Bhat et al., 2017(Bhat et al., , 2019Galanakis et al., 2020). The present study was aimed at developing highly nutritious chicken protein-based shelf-stable snacks and improving their lipid and microbial stability using Solanum nigram, a novel natural preservative and immune booster (Miraj, 2016;Rani et al., 2018).Chicken meat is not only a good source of highly bioavailable animal protein but has a favorable ratio of saturated to unsaturated