Functionalization of luminescent lanthanide complexes for biomedical applications

Recent progress of small-molecule-based theranostic agents in Alzheimer's disease

“…74 A large number of lanthanide complexes can also give off luminescence through energy transfer from the antenna groups to the metal ions. 75 On the other hand, metal complex-based drugs have already been important candidates in the drug development for the treatment of various diseases due to their fascinating properties as compared with common organic drugs, including the synergistic effect between metal ions and their ligands for interacting with biomolecular targets and tunable geometries of the complexes. 76 These features have led to the development of luminescent complex-based theranostic agents for AD.…”

Understanding Single-Molecule Magnet properties of lanthanide complexes from 4f orbital splitting

“…The electronic properties of trivalent lanthanide ions make them the focus of attention for multidisciplinary research, mainly in the fields of optics [1][2][3][4][5] and magnetism. [6][7][8][9][10][11][12][13] Lanthanide Single-Molecule Magnets (SMMs) have been intensely studied since they are considered promising candidates for technological applications, including the development of building blocks for high-density storage devices, 14,15 quantum computing, [16][17][18] and molecular spintronic devices.…”

A biotin-guided near-infrared fluorescent probe for imaging hydrogen sulfide and differentiating cancer cells

“…Compared to visible light, near-infrared (NIR) light ranging from 650 to 900 nm has many advantages for bioimaging, including lower phototoxicity to living cells, better tissue penetration, and minimum interference from background autofluorescence of biomolecules. 35,36 Recently, NIR fluorescent probes have been designed and reported to detect H 2 S in living systems. 37–45 Among those, 7-nitro-1,2,3-benzoxadiazole (NBD) amines as triggering groups were utilized frequently because of their excellent selectivity toward H 2 S over millimolar biothiols.…”